Table 2.
Cumulative incidence of colorectal cancer-specific death by potential risk factors after endoscopic stenting followed by curative resection
Variable
|
CRC-specific death (mo)
|
||
12
|
36
|
60
|
|
Age | |||
< 70 yr | 0.00 | 0.22 | 0.37 |
≥ 70 yr | 0.06 | 0.10 | 0.21 |
Sex | |||
Female | 0.04 | 0.27 | 0.45 |
Male | 0.03 | 0.09 | 0.20 |
Stent failure | |||
No | 0.04 | 0.15 | 0.31 |
Yes | 0.00 | 0.25 | 0.25 |
Surgical approach | |||
Open | 0.06 | 0.16 | 0.22 |
Laparoscopic | 0.00 | 0.15 | 0.40 |
T4 staging | |||
No | 0.04 | 0.14 | 0.18 |
Yes | 0.00 | 0.23 | 0.62 |
N2 | |||
No | 0.02 | 0.13 | 0.26 |
Yes | 0.09 | 0.27 | 0.36 |
Tumour deposit(s) | |||
No | 0.04 | 0.13 | 0.26 |
Yes | 0.00 | 0.28 | 0.40 |
Microscopic margin involvement (R1 resection) | |||
No | 0.04 | 0.15 | 0.29 |
Yes | 0.00 | 0.25 | 0.25 |
Histology | |||
Adenocarcinoma | 0.02 | 0.15 | 0.29 |
Mucinous adenocarcinoma | 0.33 | 0.33 | 0.33 |
Poorly differentiated | |||
No | 0.03 | 0.16 | 0.30 |
Yes | 0.00 | 0.00 | 0.00 |
Perineural infiltration | |||
No | 0.05 | 0.08 | 0.17 |
Yes | 0.00 | 0.30 | 0.52 |
Lymphovascular invasion | |||
No | 0.02 | 0.10 | 0.10 |
Yes | 0.06 | 0.30 | 0.64 |
Pericolic microabscess | |||
No | 0.04 | 0.14 | 0.29 |
Yes | 0.00 | 0.29 | 0.29 |
Albumin (g/dL) | |||
≥ 3.0 | 0.02 | 0.15 | 0.26 |
< 3.0 | 0.10 | 0.21 | 0.56 |
CEA (µg/L) | |||
< 5.3 | 0.00 | 0.13 | 0.22 |
≥ 5.3 | 0.06 | 0.18 | 0.35 |
ASA classification | |||
I/II | 0.02 | 0.12 | 0.28 |
III | 0.13 | 0.38 | 0.38 |
Diabetes mellitus | |||
No | 0.04 | 0.13 | 0.28 |
Yes | 0.00 | 0.25 | 0.35 |
Perioperative major complication(s) | |||
No | 0.04 | 0.15 | 0.29 |
Yes | 0.00 | - | - |
Adjuvant chemotherapy | |||
No | 0.03 | 0.07 | 0.21 |
Yes | 0.03 | 0.24 | 0.37 |
Lung-only recurrence | |||
No | 0.04 | 0.16 | 0.28 |
Yes | 0.00 | 0.13 | 0.34 |
Liver-only recurrence | |||
No | 0.04 | 0.12 | 0.24 |
Yes | 0.00 | 0.38 | 0.69 |
Peritoneum-only recurrence | |||
No | 0.00 | 0.07 | 0.12 |
Yes | 0.12 | 0.38 | 0.65 |
≥ 2 sites of recurrences | |||
No | 0.04 | 0.10 | 0.23 |
Yes | 0.00 | 0.44 | 0.63 |
CRC: Colorectal cancer; ASA: American Society of Anaesthesiologists; CEA: Carcinoembryonic antigen.