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. 2023 Feb 15;14(2):92–109. doi: 10.4239/wjd.v14.i2.92

Table 1.

Risk factors for cognitive decline in diabetes mellitus

Risk factors for cognitive decline in diabetes mellitus
Age > 60 yr Atherosclerotic cardiovascular disease
Presence of ApoE ε4 allele Uncontrolled hypertension
Long duration of diabetes Proteinuria
Poor glycaemic control/high HbA1c Dyslipidaemia
Higher fasting glucose levels Physical inactivity
Recurrent hypoglycaemic episodes Unhealthy diet
Severe insulin resistance Depression

ApoE: Apolipoprotein; HbA1c: Hemoglobin A1c.