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. 2023 Feb 28;29(8):1261–1288. doi: 10.3748/wjg.v29.i8.1261

Table 1.

Prevalence of functional constipation in children according to Rome IV and factors associated with functional constipation

Ref.
Country
Population
Sample size
Age
Method of data collection
Prevalence of FC, n
Factors associated with FC
Huang et al[139], 2021 China 4 community hospitals in Jinhua and Shanghai 2604 0-4 yr Guardian interview 92 (3.5%) Vaginal delivery (OR = 0.01, 95%CI: 0.00-0.17), forceps delivery (OR: > 999, 95%CI: 154 to > 999)
Chew et al[140], 2021 Malaysia A well child clinic, University Malaya medical center 534 1-12 mo Guardian interview 6 (1.1%) NA
Ibrahim et al[141], 2020 Egypt Randomly schools in Cairo 1082 4-18 yr NA 91 (8.4%) NA
Khayat et al[142], 2021 Saudi Arabia Public survey (random) from Western 317 3-18 yr Questionnaire by Google form/links share on social apps 15 (4.7%) Guardian characteristics, family income, gender, age, development, previous covid ìnfection (P > 0.05)
Benzamin et al[29], 2022 Bangladesh Schools of Dhaka division 707 5-16 yr Child interview and examination (face to face) 134 (19%) Female (P = 0.003), age (P = 0.001), history of FC in siblings/parents (P = 0.001), fibers intake (P = 0.002), fluid intake (P = 0.001), electronic screen time (P = 0.001)
Siajunboriboon et al[143], 2022 Thailand 2 high schools 1700 14-18 yr Child interview 138 (8.1%) Guardian characteristics, BMI, history of allergic diseases (P > 0.05)
Chia et al[144], 2022 Vietnam A government hospital and a government kindergarten 1511 0-48 mo Guardian interview and examination (face to face) 46 (3%) Male (OR = 3.6, 95%CI: 1.5-8.5), bottle feeding (OR = 18.5, 95%CI: 1.5-219.4), low income (OR = 5.8, 95%CI: 1.7-19.3)
Asia 8455 522 (6.2%)
Zwiener et al[145], 2017 United States Online survey 1075 4-18 yr Guardian interview 144 (13.4%) NA
Saps et al[146], 2018 Colombia 12 schools in 6 cities 3567 8-18 yr Child interview 382 (10.7%) NA
Robin et al[147], 2018 United States Online survey panels by CINT, United States 1255 0-18 yr Guardian interview 186 (14.8%) NA
Játiva-Mariño E et al[148], 2019 Ecuador 1 public and 1 private school 951 8-15 yr Child interview 137 (14.4%) NA
Saps et al[149], 2020 Colombia 6 outpatient clinics 1334 1-48 mo Guardian interview (face to face) 281 (15.1%) NA
Velasco-Benitez et al[150], 2020 Colombia 4 public schools 1497 10-18 yr Guardians interview 194 (13%) NA
Baaleman et al[151], 2021 Colombia A public school 118 11-18 yr Child interview 16 (13.6%) NA
Velasco-Benítez et al[152], 2021 Colombia 5 to 8 grade students in Cali 465 10-18 yr Children interview 52 (28.7%) NA
Dos Santos et al[27], 2021 Brazil Public parks and school areas 799 5-14 yr Guardian interview 163 (20.4%) Sex, type of school (P > 0.05)
de Morais et al[153], 2022 Brazil Pediatric private clinics in 5 regions 4560 0-12 mo Guardian interview 341 (7.6%) Age 162-248 d (OR = 1.41, 95%CI: 1.01-1.95), prematurity (OR = 1.44, 95%CI: 1.02-2.02)
America 15621 1896 (12.1%)
Russo et al[21], 2019 Italy General clinics 214 1 mo-17 yr Guardian/child interview(face to face) 39 (18.2%) NA
Vladimir et al[154], 2019 Russia University clinic 300 0-48 mo Guardian interview 45 (15%) NA
Steutel et al[155], 2020 Belgium, Italy, Netherland General pediatrics hospital (Belgium, Italy) and well-baby clinic (the Netherlands) 2751 0-48 mo Guardian interview and examination (face to face) 151 (5.4%) NA
Campeotto et al[156], 2020 France Private out-patient pediatricians and general practitioner 1570 0-12 mo Guardian interview and examination (face to face) 141 (9%) NA
Alonso-Bermejo et al[157], 2022 Spain A pediatric gastroenterology clinic 574 0-16 yr Guardian/child interview and examination (face to face) 41 (7.1%) NA
Beser et al[158], 2021 Turkey 9 tertiary Hospital 2383 1-12 mo Child interview and examination (face to face) 112 (4.7%) NA
Strisciuglio et al[159], 2022 6 Mediterranean countries1 Nursery schools, primary schools and secondary schools, randomly 4353 4-18 yr Guardian interview 475 (10.9%) NA
Europe 12145 1004 (8.3%)
Bellaiche et al[160], 2020 10 countries in Africa2 Children with gastrointestinal symptoms 10458 0-12 mo Guardians interview and examination (face to face) 3283 (31.4%) NA
Africa 10458 3283 (31.4%)
All over the world 46679 6704 (14.4%)
1

6 Mediterranean countries: Croatia, Greece, Israel, Italy, Macedonia, Serbia.

2

10 countries: Algeria, Cameroon, Congo, Gabon, Madagascar, Morocco, Mauritius, Ivory Coast, Senegal, Tunisia.

CINT: A global software in digital insight and research technology; FC: Functional constipation; CI: Confidence interval; OR: Odds ratio; apps: Applications; NA: Not available; BMI: Body mass index.