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. 2022 Aug 17;3:914574. doi: 10.3389/fcdhc.2022.914574

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Copyright © 2022 Torres, Corrêa, Bevilacqua, do Prado, Bandeira, Rodrigues and Gomes

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Interferon-gamma plasma levels in response to Mtb-specific antigens by non-diabetic and diabetic patients. Whole blood from study population was stimulated or not with Mtb-specific antigens (ESAT-6, CFP-10 and TB7.7) by using QuantiFERON-TB Gold in Tube (QFT-GIT) assay for 18- 24h at 37°C. A) IFN-g-Mtb-specific levels were compared among study population: (A) non-DM and pooled MD (T1D and T2D patients) or (B) non-DM, T1D and T2D. IFN-γ. Mtb-specific levels were determined by subtraction between Mtb-specific antigens minus control tube (Nil). Each dot represents an individual value. DM, Diabetes Mellitus; T1D, type-1 DM; T2D, type-2 DM.