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. 2023 Mar 14;13:4216. doi: 10.1038/s41598-023-31118-5

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Relative abundances of the five most-represented phyla (a,c) ten most-represented families based on 16S-rRNA NGS data (b,d) in each dataset at based line between Pos and Neg (T0), and at 1 + years later between before (Ss+PreT, T1) and after (Ss+PostT, T2) treatment. Relative abundance of top 35 genera presented as heatmaps (e,f).