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. 2023 Feb 13;19(1):2171233. doi: 10.1080/21645515.2023.2171233

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© 2023 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

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Figure 2. — Recombinant M. Smegmatis-based vaccine could induce the activation and maturation of antigen-presenting cells. (a) the expression level of co-stimulatory molecules on Raw264.7 and DC 2.4 cells after being infected with ZWY2-S or ZWY2-N bacteria. The red peak represents the medium control group, and the blue one represents the recombinant M. smegmatis treated group. (b) the mRNA levels of IFN-β, TNF-α, IL-6, and IL-1β in Raw264.7 and DC2.4 cells after being infected with ZWY2-S or ZWY2-N. These data were expressed as the mean ± SEM from two individual trials (*: P < .05; **: P < .01; ***: P < .001).