Table 1.
The cross-epitope between SARS-CoV-2 and M. smegmatis.
| SARS-CoV-2 | Mycolicibacterium smegmatis protein | Predicted epitope in SARS-CoV-2 protein | Allele | Rank | |
|---|---|---|---|---|---|
| SARS-CoV-2 N | ASSRSSSRSR | >WP_014877465.1 DNA translocase FtsK | 183SSRSSSRSR191 | HLA-A *31:01 | 0.13 |
| HLA-A *30:01 | 0.08 | ||||
| HLA-A *68:01 | 1.4 | ||||
| HLA-A *33:01 | 0.78 | ||||
| HLA-A *03:01 | 1.2 | ||||
| 182ASSRSSSRSR191 | HLA-A *31:01 | 0.59 | |||
| HLA-A *30:01 | 0.86 | ||||
| HLA-A *11:01 | 1.2 | ||||
| SARS-CoV-2 S | RDIADTTDAV | RDIADTTDIT (>WP_003896768.1 ectoine/hydroxyectoine ABC transporter ATP-binding protein EhuA) | 568DIADTTDAV576 | HLA-A *68:02 | 0.09 |
| HLA-A *26:01 | 0.68 | ||||
| HLA-B × 51:01 | 2 | ||||
| 567RDIADTTDAV576 | HLA-A *02:03 | 1.6 | |||
| HLA-A *02:06 | 1.6 | ||||
| ISVTTEILPV | IYVTAEILPV (>WP_011726763.1 MFS transporter) | 721SVTTEILPV729 | HLA-A *02:06 | 0.24 | |
| HLA-A *68:02 | 0.43 | ||||
| HLA-A *02:03 | 0.64 | ||||
| HLA-A *02:01 | 0.74 | ||||
| SVTTEILPVS | NPTTEILPVS (>WP_011728271.1 hydrogenase nickel incorporation protein HypB) | 721SVTTEILPV729 | HLA-A *02:06 | 0.24 | |
| HLA-A *68:02 | 0.43 | ||||
| HLA-A *02:03 | 0.64 | ||||
| HLA-A *02:01 | 0.74 | ||||
| TTEILPVSMT | TTEILPVSAR (>WP_011728271.1 hydrogenase nickel incorporation protein HypB) | 723TTEILPVSM731 | HLA-A *01:01 | 0.5 | |
| HLA-B × 35:01 | 1.1 | ||||
| HLA-A *68:02 | 1.3 | ||||
| HLA-A *26:01 | 1.5 | ||||
| HLA-B × 53:01 | 1.8 | ||||
| 724TEILPVSMT732 | HLA-B × 40:01 | 1.3 | |||
| HLA-B × 44:03 | 1.4 | ||||
| HLA-B × 44:02 | 1.8 | ||||
| 723TTEILPVSMT732 | HLA-A *68:02 | 1.9 | |||
| VTTEILPVSM | PTTEILPVSA (>WP_011728271.1 hydrogenase nickel incorporation protein HypB) | 722VTTEILPVSM731 | HLA-A *68:02 | 1.2 | |
| HLA-B × 57:01 | 1.3 | ||||
| HLA-B × 58:01 | 1.4 | ||||
| EMIAQYTSAL | EMVAQYTPAL (>WP_011729237.1 FAD-binding protein) | 869MIAQYTSAL877 | HLA-B × 08:01 | 0.31 | |
| HLA-A *68:02 | 0.34 | ||||
| HLA-A *02:03 | 0.4 | ||||
| HLA-B × 07:02 | 0.43 | ||||
| HLA-A *26:01 | 0.51 | ||||
| HLA-B × 35:01 | 0.63 | ||||
| HLA-A *02:06 | 0.68 | ||||
| HLA-A *02:01 | 0.91 | ||||
| HLA-A *32:01 | 0.98 | ||||
| HLA-B × 15:01 | 1.4 | ||||
| 868EMIAQYTSAL877 | HLA-A *26:01 | 0.89 | |||
| HLA-A *68:02 | 0.91 | ||||
| 868EMIAQYTSA876 | HLA-A *68:02 | 1.1 | |||
| HLA-B × 08:01 | 1.3 | ||||
| HLA-A *02:03 | 1.6 | ||||
| AAEIRASANL | ASAIRASANL (>WP_011728932.1 acyl-CoA dehydrogenase family protein) | 1016AEIRASANL1024 | HLA-B × 40:01 | 0.01 | |
| HLA-B × 44:03 | 0.1 | ||||
| HLA-B × 44:02 | 0.11 | ||||
| 1015AAEIRASANL1024 | HLA-B × 40:01 | 0.21 | |||
| HLA-B × 44:03 | 0.68 | ||||
| HLA-B × 44:02 | 0.65 | ||||
| RLNEVAKNLN | KLLEVAKNLN (>WP_003892935.1 propanediol/glycerol family dehydratase large subunit) | 1185RLNEVAKNL1193 | HLA-A *02:03 | 0.06 | |
| HLA-A *32:01 | 0.1 | ||||
| HLA-A *02:01 | 0.16 | ||||
| HLA-A *02:06 | 0.51 | ||||
| HLA-B × 15:01 | 1.1 | ||||
| HLA-A *30:01 | 1.4 | ||||
| HLA-A *30:02 | 1.6 | ||||
| HLA-B × 08:01 | 1.9 | ||||
| HLA-B × 07:02 | 1.9 |
Note: The underline fonts represent different amino acids.