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. 2022 Sep 21;19(4):1277–1292. doi: 10.1080/15548627.2022.2124500

Table 2.

Effect of inhibitors on NF protein levels in mouse brain.

Inhibitor effect in mouse brain on NF proteins (fold increase)
Proteins 3-MA MG-115 CAST Tg
NEFH 2.114 ± 0.020 (*) NC NC
NEFM 1.312 ± 0.017 (*) 1.408 ± 0.035 (*) 0.14 (Ref. 41)
NEFL NC NC 0.07 (Ref. 41)

Note: Effect of autophagy (3-MA), proteasome (MG115) and calpain (CAST, calpastatin) inhibitors in brains on NF protein levels in mice. The fold increases are over vehicle treated or untreated samples (one-fold increase equals to 100% increase). NC, no change. Significance is indicated in parenthesis. *p < 0.05. The data from Figure 7B, Figure 7C and from Reference 41 are compared in Table 2.