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. Author manuscript; available in PMC: 2024 Mar 1.
Published in final edited form as: Environ Res. 2022 Dec 26;220:115148. doi: 10.1016/j.envres.2022.115148

Fig. 5. Overview of Human Studies by Organ/System and Population.

Fig. 5.

Summary of the database of human studies evaluating exposures to PCB mixtures and health endpoints organized by system and population. Lists of studies included in each count can be accessed via the online interactive version of this figure (https://hawc.epa.gov/summary/visual/assessment/100500282/OverviewHumanStudies/). The online figure can be expanded to include information by endpoint category and can be filtered by organ/system (options: cardiovascular, dermal, developmental, endocrine, gastrointestinal, hematopoietic, hepatobiliary, immune system, metabolic, musculoskeletal, nervous system, ocular, reproductive, respiratory, urinary system), study design (options: case-control, cohort, cross-sectional, other), population (options: accidental, contaminated schools and other buildings, fish/marine mammal (diet), general population, occupational, residents in contaminated area, Yusho/Yu-Cheng), sex (relevant only for reproductive endpoints; options: couple, female, male), and exposure metric (options: adipose tissue, blood, breast milk, child blood, cord blood, dietary estimates, fish consumption, maternal blood, occupational/JEM, other metric [includes dust and modeled estimates], other tissue). Shading intensity corresponds with the number of studies in each category, from 1 to 167, which is the maximum number of studies in any category. JEM = job exposure matrix.