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. 2023 Mar 10;16:1027–1042. doi: 10.2147/JIR.S393850

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© 2023 Lu et al.

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Effects of Eupatilin on the survival rate, inflammation and coagulation indicators in septic mice. (A) The survival plot for the mice in each group (n=10 per group, log rank test). (B-I) The levels of TNF-α, IL-1β, IL-6, TF, TAT, PAI-1, D-dimer, and fibrinogen in mice plasma were detected by ELISA (n≥3 per group, one-way ANOVA test). Mice were pretreated with Eup (10mg/kg) by gavage for 2 hours before CLP modeling for 24 hours. *p < 0.05, **p < 0.01, ***p < 0.001, versus SHAM group; #p < 0.05, ##p < 0.01, ###p < 0.001, versus CLP group.