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. 2023 Mar 14;6(1):ooad016. doi: 10.1093/jamiaopen/ooad016

Table 4.

PASC vs COVID negative comparison TreeScan results

Cut Node Tree level Log likelihood ratio P value N cases observed N cases expected Percent excess cases
A00–B99 Certain infections and parasitic diseases
10 B90–B94 Sequelae of infectious and parasitic diseases 2 281.31 .001 157 26.17 499.92
11 B94 Sequelae of other and unspecified infectious and parasitic diseases 3 281.31 .001 157 26.17 499.92
12 B94.8 Sequelae of other specified infectious and parasitic diseases 4 275.93 .001 154 25.67 499.92
15 A00–B99 Certain infections and parasitic diseases 1 239.90 .001 797 132.83 202.64
76 B95–B98 Bacterial, viral, and other infectious agents 2 35.38 .001 190 31.67 155.76
96 B25–B34 Other viral diseases 2 27.51 .001 162 27.00 148.15
116 B97 Viral agents as the cause of diseases classified elsewhere 3 23.01 .001 81 13.50 196.30
128 B34 Viral infection of unspecified site 3 20.49 .001 121 20.17 147.89
214 B97.2 Coronavirus as the cause of diseases classified elsewhere 4 12.54 .002 7 1.17 498.29
215 B97.29 Other coronavirus as the cause of diseases classified elsewhere 5 12.54 .002 7 1.17 498.29
217 A30–A49 Other bacterial diseases 2 12.54 .002 48 8.00 187.50
240 B97.89 Other viral agents as the cause of diseases classified elsewhere 5 11.38 .003 54 9.00 166.67
246 B34.8 Other viral infections of unspecified site 4 11.14 .006 18 3.00 300.00
252 B97.8 Other viral agents as the cause of diseases classified elsewhere 4 10.98 .006 55 9.17 161.72
286 B25 Cytomegaloviral disease 3 9.69 .020 10 1.67 379.04
D50–D89 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
33 D50–D89 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism 1 91.55 .001 623 103.83 136.93
50 D89.89 Other specified disorders involving the immune mechanism, not elsewhere classified 5 55.61 .001 42 7.00 442.86
55 D89 Other disorders involving the immune mechanism, not elsewhere classified 3 48.34 .001 83 13.83 290.46
63 D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified 4 43.65 .001 73 12.17 294.41
65 D80–D89 Certain disorders involving the immune mechanism 2 42.19 .001 221 36.83 157.94
158 D64.9 Anemia, unspecified 4 16.91 .001 49 8.17 218.24
161 D60–D64 Aplastic and other anemias 2 16.73 .001 129 21.50 127.91
185 D64 Other anemias 3 14.59 .001 70 11.67 165.64
200 D55–D59 Hemolytic anemias 2 13.41 .001 37 6.17 224.15
210 D65–D69 Coagulation defects, purpura, and other hemorrhagic conditions 2 12.71 .001 75 12.50 148.00
211 D57 Sickle-cell disorders 3 12.64 .001 24 4.00 275.00
E00–E90 Endocrine, nutritional, and metabolic diseases
30 E00–E90 Endocrine, nutritional, and metabolic diseases 1 98.96 .001 1294 215.67 96.13
42 E70–E88 Metabolic disorders 2 73.49 .001 491 81.83 138.30
71 E87 Other disorders of fluid, electrolyte, and acid-base balance 3 40.29 .001 105 17.50 231.43
119 E86 Volume depletion 3 22.80 .001 72 12.00 208.33
123 E86.0 Dehydration 4 22.21 .001 70 11.67 208.48
129 E65–E68 Obesity and other hyperalimentation 2 20.43 .001 189 31.50 115.87
133 E66 Overweight and obesity 3 19.94 .001 183 30.50 116.39
203 E87.7 Fluid overload 4 13.17 .001 26 4.33 269.52
208 E66.9 Obesity, unspecified 4 12.92 .001 78 13.00 146.15
212 E87.70 Fluid overload, unspecified 5 12.64 .001 24 4.00 275.00
239 E87.5 Hyperkalemia 4 11.38 .003 9 1.50 433.33
261 E83 Disorders of mineral metabolism 3 10.61 .012 129 21.50 100.00
270 E50–E64 Other nutritional deficiencies 2 10.33 .013 147 24.50 91.84
F00–F99 Mental and behavioral disorders
27 F00–F99 Mental and behavioral disorders 1 108.72 .001 1973 328.83 80.64
51 F40–F48 Neurotic, stress-related, and somatoform disorders 2 54.50 .001 590 98.33 106.45
81 F41 Other anxiety disorders 3 30.21 .001 254 42.33 122.06
94 F80–F89 Disorders of psychological development 2 27.72 .001 475 79.17 83.15
111 F41.9 Anxiety disorder, unspecified 4 24.05 .001 180 30.00 130.00
171 F44 Dissociative and conversion disorders 3 15.83 .001 28 4.67 285.44
189 F00–F09 Organic, including symptomatic, mental disorders 2 14.49 .001 27 4.50 277.78
242 F80 Specific developmental disorders of speech and language 3 11.29 .003 114 19.00 110.53
253 F69 Unspecified disorder of adult personality and behavior 3 10.75 .011 6 1.00 500.00
267 F90–F98 Behavioral and emotional disorders with onset usually occurring in childhood and adolescence 2 10.45 .013 198 33.00 78.79
275 F32 Depressive episode 3 10.19 .013 182 30.33 81.34
294 F43 Reaction to severe stress, and adjustment disorders 3 9.45 .022 222 37.00 70.27
G00–G99 Diseases of the nervous system
13 G00–G99 Diseases of the nervous system 1 259.71 .001 2311 385.17 118.35
25 G40–G47 Episodic and paroxysmal disorders 2 122.60 .001 1475 245.83 100.55
29 G89–G99 Other disorders of the nervous system 2 101.22 .001 520 86.67 159.61
48 G43 Migraine 3 57.17 .001 318 53.00 152.83
52 G47 Sleep disorders 3 53.89 .001 501 83.50 115.57
53 G89 Pain, not elsewhere classified 3 52.73 .001 309 51.50 148.54
57 G89.2 Chronic pain, not elsewhere classified 4 47.17 .001 229 38.17 164.61
59 G89.29 Other chronic pain 5 46.20 .001 228 38.00 163.16
73 G44 Other headache syndromes 3 39.27 .001 95 15.83 241.12
78 G00–G09 Inflammatory diseases of the central nervous system 2 31.56 .001 51 8.50 300.00
82 G43.0 Migraine without aura 4 30.11 .001 131 21.83 174.85
99 G90 Disorders of autonomic nervous system 3 26.46 .001 44 7.33 295.63
101 G44.5 Complicated headache syndromes 4 25.75 .001 24 4.00 400.00
106 G93 Other disorders of brain 3 24.61 .001 138 23.00 152.17
112 G04 Encephalitis, myelitis, and encephalomyelitis 3 23.84 .001 32 5.33 331.52
131 G47.3 Sleep apnea 4 20.12 .001 284 47.33 92.27
135 G44.52 New daily persistent headache (NDPH) 5 19.39 .001 20 3.33 380.48
144 G43.01 Migraine without aura, intractable 5 18.74 .001 46 7.67 238.98
148 G47.9 Sleep disorder, unspecified 4 18.19 .001 75 12.50 180.00
149 G04.8 Other encephalitis, myelitis, and encephalomyelitis 4 18.05 .001 21 3.50 357.14
159 G90.9 Disorder of the autonomic nervous system, unspecified 4 16.87 .001 22 3.67 335.97
168 G93.3 Postviral fatigue syndrome 4 16.13 .001 9 1.50 500.00
176 G43.019 Migraine without aura, intractable, without status migrainosus 6 15.24 .001 37 6.17 240.36
207 G43.00 Migraine without aura, not intractable 5 13.01 .001 85 14.17 139.94
209 G93.4 Other and unspecified encephalopathy 4 12.87 .001 64 10.67 162.42
223 G43.009 Migraine without aura, not intractable, without status migrainosus 6 12.37 .002 76 12.67 144.67
231 G44.89 Other headache syndrome 5 11.74 .002 15 2.50 340.00
235 G44.8 Other specified headache syndromes 4 11.62 .002 20 3.33 290.39
241 G47.30 Sleep apnea, unspecified 5 11.38 .003 54 9.00 166.67
258 G04.81 Other encephalitis and encephalomyelitis 5 10.68 .012 16 2.67 311.99
272 G90.1 Familial dysautonomia [Riley-Day] 4 10.27 .013 14 2.33 329.18
292 G93.40 Encephalopathy, unspecified 5 9.50 .022 20 3.33 260.36
297 G25 Other extrapyramidal and movement disorders 3 9.40 .023 32 5.33 200.19
H00–H59 Diseases of the eye and adnexa
238 H53.1 Subjective visual disturbances 4 11.44 .002 13 2.17 360.83
256 H53.14 Visual discomfort 5 10.75 .011 6 1.00 500.00
291 H53–H54 Visual disturbances and blindness 2 9.59 .020 138 23.00 91.30
298 H53 Visual disturbances 3 9.38 .023 114 19.00 100.00
I00–I99 Diseases of the circulatory system
32 I00–I99 Diseases of the circulatory system 1 95.20 .001 682 113.67 133.13
75 I30–I52 Other forms of heart disease 2 35.57 .001 193 32.17 154.90
151 I95.1 Orthostatic hypotension 4 17.71 .001 17 2.83 394.70
157 I95–I99 Other and unspecified disorders of the circulatory system 2 16.93 .001 52 8.67 211.42
163 I95 Hypotension 3 16.47 .001 38 6.33 247.55
194 I49 Other cardiac arrhythmias 3 14.11 .001 48 8.00 200.00
213 I60–I69 Cerebrovascular diseases 2 12.58 .001 79 13.17 142.98
226 I10–I19 Hypertensive diseases 2 12.03 .002 131 21.83 106.14
228 I26–I28 Pulmonary heart disease and diseases of pulmonary circulation 2 11.95 .002 46 7.67 186.83
247 I49.8 Other specified cardiac arrhythmias 4 11.09 .006 29 4.83 231.26
290 I51 Complications and ill-defined descriptions of heart disease 3 9.61 .020 38 6.33 184.36
J00–J99 Diseases of the respiratory system
14 J00–J99 Diseases of the respiratory system 1 246.45 .001 2185 364.17 118.58
35 J40–J47 Chronic lower respiratory diseases 2 86.15 .001 682 113.67 126.09
36 J45 Asthma 3 83.40 .001 661 110.17 126.01
64 J96–J99 Other diseases of the respiratory system 2 43.41 .001 282 47.00 140.43
67 J30–J39 Other diseases of upper respiratory tract 2 41.35 .001 480 80.00 102.50
69 J45.9 Other and unspecified asthma 4 40.97 .001 193 32.17 167.33
74 J09–J18 Influenza and pneumonia 2 35.85 .001 122 20.33 200.05
79 J45.909 Unspecified asthma, uncomplicated 6 31.00 .001 139 23.17 171.90
85 J45.90 Unspecified asthma 5 29.52 .001 160 26.67 154.97
103 J96 Respiratory failure, not elsewhere classified 3 25.29 .001 154 25.67 145.42
114 J00–J06 Acute upper respiratory infections 2 23.47 .001 460 76.67 77.38
117 J45.4 Moderate persistent asthma 4 22.92 .001 111 18.50 164.86
118 J96.0 Acute respiratory failure 4 22.82 .001 57 9.50 236.84
121 J12.8 Other viral pneumonia 4 22.55 .001 20 3.33 410.51
122 J12 Viral pneumonia, not elsewhere classified 3 22.38 .001 31 5.17 325.53
126 J45.40 Moderate persistent asthma, uncomplicated 5 21.38 .001 91 15.17 176.86
134 J12.82 Pneumonia due to coronavirus disease 2019 5 19.71 .001 11 1.83 501.09
139 J98 Other respiratory disorders 3 19.14 .001 125 20.83 140.04
166 J38 Diseases of vocal cords and larynx, not elsewhere classified 3 16.32 .001 47 7.83 219.28
174 J45.30 Mild persistent asthma, uncomplicated 5 15.34 .001 130 21.67 121.50
188 J03 Acute tonsillitis 3 14.49 .001 27 4.50 277.78
196 J35 Chronic diseases of tonsils and adenoids 3 13.85 .001 65 10.83 167.77
199 J96.01 Acute respiratory failure with hypoxia 5 13.45 .001 34 5.67 235.10
216 J22 Unspecified acute lower respiratory infection 3 12.54 .002 7 1.17 498.29
224 J45.99 Other asthma 5 12.25 .002 33 5.50 227.27
232 J80–J84 Other respiratory diseases principally affecting the interstitium 2 11.73 .002 28 4.67 242.61
236 J45.3 Mild persistent asthma 4 11.60 .002 166 27.67 91.54
244 J20–J22 Other acute lower respiratory infections 2 11.26 .006 41 6.83 192.83
254 J15.21 Pneumonia due to Staphylococcus aureus 5 10.75 .011 6 1.00 500.00
255 J15.2 Pneumonia due to Staphylococcus 4 10.75 .011 6 1.00 500.00
257 J38.3 Other diseases of vocal cords 4 10.68 .012 16 2.67 311.99
262 J15 Bacterial pneumonia, not elsewhere classified 3 10.61 .013 24 4.00 250.00
264 J45.2 Mild intermittent asthma 4 10.55 .013 180 30.00 83.33
284 J03.0 Streptococcal tonsillitis 4 9.71 .017 8 1.33 426.32
285 J03.01 Acute recurrent streptococcal tonsillitis 5 9.71 .017 8 1.33 426.32
288 J03.91 Acute recurrent tonsillitis, unspecified 5 9.69 .020 10 1.67 379.04
295 J45.20 Mild intermittent asthma, uncomplicated 5 9.44 .022 143 23.83 88.84
K00–K93 Diseases of the digestive system
77 K00–K93 Diseases of the digestive system 1 35.37 .001 1701 283.50 48.15
155 K20–K31 Diseases of oesophagus, stomach, and duodenum 2 17.20 .001 343 57.17 76.67
179 K55–K64 Other diseases of intestines 2 14.87 .001 625 104.17 51.68
225 K59.0 Constipation 4 12.19 .002 505 84.17 52.07
249 K59 Other functional intestinal disorders 3 11.01 .006 521 86.83 48.57
250 K70–K77 Diseases of liver 2 10.98 .006 62 10.33 151.69
274 K31.8 Other specified diseases of stomach and duodenum 4 10.23 .013 50 8.33 164.11
304 K31 Other diseases of stomach and duodenum 3 8.97 .031 57 9.50 142.11
L00–L99 Diseases of the skin and subcutaneous tissue
62 L00–L99 Diseases of the skin and subcutaneous tissue 1 44.06 .001 766 127.67 82.50
138 L80–L99 Other disorders of the skin and subcutaneous tissue 2 19.14 .001 198 33.00 109.09
222 L89 Pressure ulcer 3 12.42 .002 27 4.50 255.56
233 L20–L30 Dermatitis and eczema 2 11.69 .002 248 41.33 74.21
268 L49–L54 Urticaria and erythema 2 10.41 .013 53 8.83 160.48
M00–M99 Diseases of the musculoskeletal system and connective tissue
18 M00–M99 Diseases of the musculoskeletal system and connective tissue 1 215.57 .001 3089 514.83 91.52
38 M79 Other and unspecified soft tissue disorders, not elsewhere classified 3 81.52 .001 370 61.67 170.80
39 M70–M79 Other soft tissue disorders 2 79.67 .001 402 67.00 161.19
41 M20–M25 Other joint disorders 2 77.45 .001 1113 185.50 91.37
46 M25.5 Pain in joint 4 58.78 .001 464 77.33 126.30
49 M25 Other joint disorder, not elsewhere classified 3 57.07 .001 701 116.83 99.44
60 M79.1 Myalgia 4 45.14 .001 109 18.17 241.22
70 M79.6 Pain in limb, hand, foot, fingers, and toes 4 40.67 .001 211 35.17 158.74
80 M86–M90 Other osteopathies 2 30.38 .001 95 15.83 209.54
90 M79.10 Myalgia, unspecified site 5 28.35 .001 42 7.00 314.29
93 M50–M54 Other dorsopathies 2 27.90 .001 220 36.67 126.34
97 M54 Dorsalgia 3 26.87 .001 197 32.83 131.50
100 M60–M63 Disorders of muscles 2 26.43 .001 375 62.50 92.00
102 M62 Other disorders of muscle 3 25.69 .001 366 61.00 91.80
107 M25.50 Pain in unspecified joint 5 24.50 .001 49 8.17 267.20
125 M79.60 Pain in limb, unspecified 5 22.11 .001 96 16.00 175.00
137 M25.56 Pain in knee 5 19.22 .001 174 29.00 117.24
142 M30–M36 Systemic connective tissue disorders 2 18.96 .001 90 15.00 166.67
143 M62.8 Other specified disorders of muscle 4 18.80 .001 325 54.17 82.76
153 M79.18 Myalgia, other site 5 17.23 .001 64 10.67 190.53
162 M35 Other systemic involvement of connective tissue 3 16.47 .001 38 6.33 247.55
164 M02.30 Reiter’s disease, unspecified site 5 16.45 .001 12 2.00 450.00
167 M00–M02 Infectious arthropathies 2 16.28 .001 18 3.00 366.67
169 M24 Other specific joint derangements 3 16.00 .001 147 24.50 116.33
183 M89 Other disorders of bone 3 14.60 .001 38 6.33 231.75
186 M02.3 Reiter’s disease 4 14.54 .001 15 2.50 380.00
187 M02 Postinfective and reactive arthropathies 3 14.54 .001 15 2.50 380.00
190 M99 Biomechanical lesions, not elsewhere classified 3 14.33 .001 8 1.33 501.50
191 M99–M99 Biomechanical lesions, not elsewhere classified 2 14.33 .001 8 1.33 501.50
192 M99.0 Segmental and somatic dysfunction 4 14.33 .001 8 1.33 501.50
204 M62.81 Muscle weakness (generalized) 5 13.11 .001 163 27.17 98.75
221 M79.66 Pain in lower leg 5 12.42 .002 27 4.50 255.56
245 M35.7 Hypermobility syndrome 4 11.17 .006 26 4.33 246.42
263 M86 Osteomyelitis 3 10.58 .013 36 6.00 200.00
271 M24.9 Joint derangement, unspecified 4 10.27 .013 19 3.17 278.55
277 M79.605 Pain in left leg 6 10.08 .013 37 6.17 191.73
281 M79.662 Pain in left lower leg 6 9.92 .015 12 2.00 350.00
287 M89.1 Physeal arrest 4 9.69 .020 10 1.67 379.04
300 M25.561 Pain in right knee 6 9.34 .024 90 15.00 113.33
301 M21 Other acquired deformities of limbs 3 9.30 .024 205 34.17 72.67
N00–N99 Diseases of the genitourinary system
130 N00–N99 Diseases of the genitourinary system 1 20.35 .001 768 128.00 54.69
195 N17 Acute kidney failure 3 13.99 .001 39 6.50 223.08
220 N76 Other inflammation of vagina and vulva 3 12.42 .002 27 4.50 255.56
278 N17.9 Acute kidney failure, unspecified 4 9.99 .013 34 5.67 199.82
293 N80–N98 Noninflammatory disorders of female genital tract 2 9.46 .022 263 43.83 64.27
303 N70–N77 Inflammatory diseases of female pelvic organs 2 9.03 .031 36 6.00 183.33
Q00–Q99 Congenital malformations, deformations, and chromosomal abnormalities
182 Q79 Congenital malformations of musculoskeletal system, not elsewhere classified 3 14.63 .001 47 7.83 206.51
198 Q79.6 Ehlers-Danlos syndromes 4 13.45 .001 43 7.17 206.83
202 Q00–Q99 Congenital malformations, deformations, and chromosomal abnormalities 1 13.18 .001 700 116.67 45.71
260 Q20–Q28 Congenital malformations of the circulatory system 2 10.62 .012 93 15.50 119.35
R00–R99 Symptoms, signs, and abnormal clinical and laboratory findings, not elsewhere classified
1 R00–R99 Symptoms, signs, and abnormal clinical and laboratory findings, not elsewhere classified 1 1327.81 .001 6736 1122.67 160.72
6 R00–R09 Symptoms and signs involving the circulatory and respiratory systems 2 608.75 .001 1533 255.50 235.81
7 R06.0 Dyspnea 4 334.81 .001 306 51.00 403.92
8 R50–R69 General symptoms and signs 2 326.26 .001 1791 298.50 153.94
9 R06 Abnormalities of breathing 3 313.01 .001 546 91.00 287.91
19 R53 Malaise and fatigue 3 197.77 .001 387 64.50 270.54
20 R53.8 Other malaise and fatigue 4 189.63 .001 326 54.33 290.21
21 R10–R19 Symptoms and signs involving the digestive system and abdomen 2 154.74 .001 1400 233.33 117.29
22 R40–R46 Symptoms and signs involving cognition, perception, emotional state, and behavior 2 142.00 .001 628 104.67 173.24
23 R07 Pain in throat and chest 3 137.91 .001 209 34.83 310.57
24 R06.02 Shortness of breath 5 137.06 .001 119 19.83 414.37
26 R53.83 Other fatigue 5 121.77 .001 209 34.83 290.47
28 R06.00 Dyspnea, unspecified 5 103.08 .001 92 15.33 408.81
31 R06.09 Other forms of dyspnea 5 96.99 .001 71 11.83 449.45
34 R07.9 Chest pain, unspecified 4 88.76 .001 120 20.00 330.00
37 R42 Dizziness and giddiness 3 81.90 .001 155 25.83 275.53
40 R51 Headache 3 77.98 .001 188 31.33 241.53
43 R51.9 Headache, unspecified 4 71.08 .001 167 27.83 244.95
44 R00 Abnormalities of heart beat 3 70.07 .001 160 26.67 248.71
45 R10 Abdominal and pelvic pain 3 62.08 .001 564 94.00 117.02
47 R05 Cough 3 57.90 .001 295 49.17 160.32
54 R25–R29 Symptoms and signs involving the nervous and musculoskeletal systems 2 52.31 .001 321 53.50 144.86
56 R07.89 Other chest pain 5 47.31 .001 62 10.33 335.62
58 R07.8 Other chest pain 4 46.89 .001 72 12.00 308.33
61 R11 Nausea and vomiting 3 44.98 .001 344 57.33 128.50
66 R00.2 Palpitations 4 41.77 .001 65 10.83 306.28
68 R09 Other symptoms and signs involving the circulatory and respiratory system 3 41.14 .001 238 39.67 149.56
72 R53.82 Chronic fatigue, unspecified 5 40.04 .001 57 9.50 321.05
84 R06.8 Other abnormalities of breathing 4 29.75 .001 188 31.33 142.58
86 R50 Fever of other and unknown origin 3 29.25 .001 175 29.17 146.83
87 R90–R96 Abnormal findings on diagnostic imaging and in function studies, without diagnosis 2 29.08 .001 216 36.00 130.56
88 R00.0 Tachycardia, unspecified 4 28.77 .001 68 11.33 244.22
89 R53.81 Other malaise 5 28.50 .001 60 10.00 260.00
91 R70–R79 Abnormal findings on examination of blood, without diagnosis 2 28.31 .001 230 38.33 124.37
92 R20–R23 Symptoms and signs involving the skin and subcutaneous tissue 2 28.25 .001 200 33.33 134.02
95 R29 Other symptoms and signs involving the nervous and musculoskeletal systems 3 27.58 .001 191 31.83 135.63
98 R05.9 Cough, unspecified 4 26.70 .001 150 25.00 152.00
104 R55 Syncope and collapse 3 25.15 .001 80 13.33 207.58
105 R43 Disturbances of smell and taste 3 24.64 .001 36 6.00 316.67
108 R09.0 Asphyxia and hypoxemia 4 24.49 .001 72 12.00 216.67
109 R09.02 Hypoxemia 5 24.49 .001 72 12.00 216.67
110 R50.9 Fever, unspecified 4 24.46 .001 142 23.67 149.26
113 R19 Other symptoms and signs involving the digestive system and abdomen 3 23.76 .001 144 24.00 145.83
115 R30–R39 Symptoms and signs involving the urinary system 2 23.09 .001 254 42.33 105.53
120 R41 Other symptoms and signs involving cognitive functions and awareness 3 22.70 .001 122 20.33 155.78
127 R68 Other general symptoms and signs 3 20.63 .001 103 17.17 162.09
132 R10.8 Other abdominal pain 4 20.08 .001 167 27.83 122.78
136 R11.10 Vomiting, unspecified 5 19.32 .001 162 27.00 122.22
140 R10.9 Unspecified abdominal pain 4 19.12 .001 107 17.83 152.38
141 R10.84 Generalized abdominal pain 5 19.04 .001 163 27.17 120.83
145 R06.83 Snoring 5 18.63 .001 84 14.00 171.43
146 R13 Aphagia and dysphagia 3 18.48 .001 250 41.67 94.38
147 R13.1 Dysphagia 4 18.48 .001 250 41.67 94.38
150 R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems 4 17.74 .001 160 26.67 117.47
152 R20 Disturbances of skin sensation 3 17.38 .001 34 5.67 270.37
154 R11.1 Vomiting 4 17.22 .001 198 33.00 103.03
160 R46 Symptoms and signs involving appearance and behavior 3 16.74 .001 103 17.17 144.61
165 R29.90 Unspecified symptoms and signs involving the nervous system 5 16.45 .001 12 2.00 450.00
170 R46.8 Other symptoms and signs involving appearance and behavior 4 15.86 .001 102 17.00 141.18
173 R68.8 Other general symptoms and signs 4 15.36 .001 89 14.83 149.49
175 R10.1 Pain localized to upper abdomen 4 15.34 .001 130 21.67 121.50
177 R68.89 Other general symptoms and signs 5 15.13 .001 79 13.17 158.16
178 R11.2 Nausea with vomiting, unspecified 4 15.13 .001 62 10.33 180.74
181 R29.9 Unspecified symptoms and signs involving the nervous and musculoskeletal systems 4 14.75 .001 17 2.83 359.36
184 R11.0 Nausea 4 14.59 .001 84 14.00 150.00
193 R19.7 Diarrhea, unspecified 4 14.33 .001 92 15.33 141.36
197 R52 Pain, unspecified 3 13.61 .001 49 8.17 193.76
201 R63 Symptoms and signs concerning food and fluid intake 3 13.24 .001 274 45.67 75.17
205 R53.1 Weakness 4 13.11 .001 60 10.00 170.00
206 R20.2 Paresthesia of skin 4 13.06 .001 10 1.67 438.92
219 R13.10 Dysphagia, unspecified 5 12.46 .002 98 16.33 126.58
227 R10.13 Epigastric pain 5 12.03 .002 77 12.83 141.62
229 R04 Hemorrhage from respiratory passages 3 11.95 .002 56 9.33 167.95
234 R05.3 Chronic cough 4 11.67 .002 31 5.17 228.82
237 R31 Hematuria 3 11.49 .002 47 7.83 180.97
243 R09.81 Nasal congestion 5 11.29 .003 118 19.67 108.44
248 R26 3 11.09 .006 29 4.83 231.26
251 R10.3 Pain localized to other parts of lower abdomen 4 10.98 .006 148 24.67 94.57
265 R40 Somnolence, stupor, and coma 3 10.52 .013 33 5.50 209.09
266 R01 Cardiac murmurs and other cardiac sounds 3 10.52 .013 27 4.50 233.33
269 R46.89 Other symptoms and signs involving appearance and behavior 5 10.35 .013 94 15.67 116.98
273 R79 Other abnormal findings of blood chemistry 3 10.25 .013 139 23.17 94.22
276 R41.8 Other symptoms and signs involving cognitive functions and awareness 4 10.10 .013 91 15.17 117.53
279 R59 Enlarged lymph nodes 3 9.99 .013 34 5.67 199.82
280 R43.9 Unspecified disturbances of smell and taste 4 9.92 .015 12 2.00 350.00
282 R93 Abnormal findings on diagnostic imaging of other body structures 3 9.84 .016 51 8.50 158.82
283 R46.81 Obsessive-compulsive behavior 5 9.71 .017 8 1.33 426.32
289 R04.0 Epistaxis 4 9.65 .020 48 8.00 162.50
299 R01.1 Cardiac murmur, unspecified 4 9.37 .023 23 3.83 239.43
S00–T98 Injury, poisoning, and certain other consequences of external causes
302 T86 Complications of transplanted organs and tissue 3 9.19 .027 60 10.00 140.00
U00–U95 Codes for special purposes
2 U00–U49 Provisional assignment of new diseases of uncertain etiology or emergency use 2 853.05 .001 481 80.17 498.73
3 U00–U95 Codes for special purposes 1 853.05 .001 481 80.17 498.73
4 U09 Post COVID-19 condition 3 614.57 .001 343 57.17 499.97
5 U09.9 Post COVID-19 condition, unspecified 4 614.57 .001 343 57.17 499.97
16 U07 3 239.73 .001 138 23.00 495.65
17 U07.1 Emergency use of U07.1 | COVID-19 4 239.73 .001 138 23.00 495.65
V01–Y98 External causes of morbidity and mortality
230 V01–Y98 External causes of morbidity and mortality 1 11.89 .002 190 31.67 86.30
296 V00–V99 Transport accidents 2 9.41 .022 156 26.00 84.62
Z00–Z99 Factors influencing health status and contact with health services
83 Z00–Z99 Factors influencing health status and contact with health services 1 29.88 .001 1843 307.17 42.27
124 Z69–Z76 Persons encountering health services in other circumstances 2 22.15 .001 258 43.00 102.33
156 Z99.8 Dependence on other enabling machines and devices 4 17.06 .001 81 13.50 166.67
172 Z99.81 Dependence on supplemental oxygen 5 15.74 .001 45 7.50 220.00
180 Z89 Acquired absence of limb 3 14.75 .001 11 1.83 446.45
218 Z99 Dependence on enabling machines and devices, not elsewhere classified 3 12.52 .002 133 22.17 107.49
259 Z77–Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status 2 10.62 .012 579 96.50 45.08