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. 2023 Feb 21;8(2):e10443. doi: 10.1002/btm2.10443

FIGURE 1.

FIGURE 1

IL‐17A producing γδ lymphocytes in an IL‐17A reporter mice model with PD is decreased after repeated hWJCM injections. (a) Experimental procedure indicating subcutaneous administration of 100 μl of hWJCM for 9 consecutive days, created with BioRender.com. (b) Gross examination. For comparison, gross dorsal skin of mice in each group was photographed at Day 13, 24 h postceasing IMQ treatment. (c) Flow cytometry analysis at Day 13 showing the percentage of γδ lymphocytes in each group. (d) Flow cytometry analysis at Day 13 showing the percentage of IL‐17‐producing γδ lymphocytes in each group. (e) TNF‐α levels present in the skin. (f) Number of cells per gram of skin in mice from each group. Data were analyzed with test for differences per 10,000 paired permutations, α = 0.05, n = 4.