Fig 5. Differential accessibility analysis.

(A) Volcano plot of open chromatin peaks; peaks with FDR adjusted p<0.05 and |log₂FC|>1 were colored by direction of accessibility change, positive log₂FC indicate greater accessibility in cerebral cortex. (B) Scatter plot of log₂FC from DEG and DAR analyses, Pearson correlation r = 0.4. (C) Scatter plot of log₂FC from DEG and DAR analyses, only those with both FDR adjusted p<0.05 were plotted; shaded areas indicate regions where either FC_DEG or FC_DAR was under 2-fold.