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. Author manuscript; available in PMC: 2023 Nov 23.
Published in final edited form as: Cell. 2022 Nov 23;185(24):4587–4603.e23. doi: 10.1016/j.cell.2022.10.016

Figure 6: HAQERs are enriched near genetic variants linked to human disease.

Figure 6:

(A) Experimental design. For each GWAS catalog variant, we identified all linked variants (R2 > 0.7). We calculated overlap enrichments between HAQERs and the set of all linked variation for all SNPs associated with a GWAS trait. (B) FDR-corrected p-values for overlap enrichments between HAQERs and GWAS Catalog traits. The dotted line marks pAdj = 0.05. (C) Representative overlaps between HAQERs (red) and 1000 Genomes variants (purple) linked to GWAS catalog variants (black labels). See also Figure S6.