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. 2023 Feb 15;13(3):e2883. doi: 10.1002/brb3.2883

FIGURE 5.

FIGURE 5

Clinical symptom correlation results across all participants over 3 combined neurofeedback training runs. Results indicate brain areas whose connectivity with the PPI seed region—the left or right PCC—are correlated with participant scores on clinical measures during regulate as compared to view conditions. (a) CAPS scores are positively correlated with connectivity between the right PCC and both the right amygdala and left anterior insula. (b) Connectivity between both PCC seeds and the right amygdala are positively correlated with BDI scores. (c) MDI scores are positively correlated with right PCC‐right amygdala connectivity. (d) Connectivity between both PCC seeds and the right amygdala are positively correlated with DERS scores. (e) CTQ scores are positively correlated with connectivity between the left PCC and both the right ventral striatum/nucleus accumbens and the dmPFC. All results are evaluated at the FWE‐peak corrected threshold for multiple comparisons (p < .05, k = 10). NFB = neurofeedback, PCC = posterior cingulate cortex, dmPFC = dorsomedial prefrontal cortex, CAPS = Clinician‐administered PTSD Scale, BDI = Beck's Depression Inventory, MDI = Multiscale Dissociation Inventory, DERS = Difficulties in Emotion Regulation Scale, CTQ = Childhood Trauma Questionnaire.