TABLE 3.
MNI coordinate | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
Comparison | Contrast | PCC seed | Brain region | k | x | y | z | t‐Stat. | z‐Score | p‐FWE peak |
Whole‐brain | ||||||||||
Within‐group | ||||||||||
Healthy controls | View > Reg | Left | ns | |||||||
View > Reg | Right | ns | ||||||||
Reg > View | Left | Calcarine cortex/cuneus | 1272 | 14 | −64 | 6 | 5.86 | 5.13 | .019 | |
Reg > View | Right | ns | ||||||||
PTSD | View > Reg | Left | ns | |||||||
View > Reg | Right | ns | ||||||||
Reg > View | Left | ns | ||||||||
Reg > View | Right | ns | ||||||||
Between‐group | ||||||||||
PTSD > Healthy controls | View > Reg | Left | ns | |||||||
View > Reg | Right | ns | ||||||||
Reg > View | Left | ns | ||||||||
Reg > View | Right | ns | ||||||||
ROIs | ||||||||||
Within‐group | ||||||||||
Healthy controls | View > Reg | Left | ns | |||||||
View > Reg | Right | ns | ||||||||
Reg > View | Left | ns | ||||||||
Reg > View | Right | ns | ||||||||
PTSD | View > Reg | Left | ns | |||||||
View > Reg | Right | ns | ||||||||
Reg > View | Left | ns | ||||||||
Reg > View | Right | ns | ||||||||
Between‐group | ||||||||||
PTSD > Healthy controls | View > Reg | Left | ns | |||||||
View > Reg | Right | ns | ||||||||
Reg > View | Left | ns | ||||||||
Reg > View | Right | ns |
Note: Within‐ and between‐group differences in functional connectivity of the PCC (left and right seeds) during the neurofeedback transfer run. Reported results for whole‐brain and ROI analyses are at a significance threshold of p‐FWE peak‐level < .05, k = 10. The comparison column lists each group comparison, and the contrast column indicates the direction in which the regulate and view conditions are being contrasted (i.e., view > regulate or regulate > view). The brain region, cluster size (k), MNI coordinates (x, y, z), t‐statistic (t‐stat.), z‐Score, and significance (p‐FWE peak) of each significant peak result are included as columns. PCC = posterior cingulate cortex, FWE = family‐wise error, PTSD = posttraumatic stress disorder, Reg = regulate, ns = nonsignificant.