Table 2. Demographics, MRI findings, and clinical data considering the three forms of the disease.
| Variable | Clinical types | p - value | |||
|---|---|---|---|---|---|
| PP | RR | SP | |||
| Patients (%) | – | 9 (9.5) | 73 (76.8) | 13 (13.7) | – |
| Gender | M (%) | 7 (20.0) | 24 (68.6) | 4 (11.4) | < 0.03 |
| F (%) | 2 (3.3) | 49 (81.7) | 9 (15.0) | N | |
| Periventricular (LL) | Mean (SD) | 16.9(21.9) | 12.9(1.5) | 32.9(5.5) | N |
| Periventricular (NL) | Mean (SD) | 31(12.2) | 38.(26.5) | 46.2(22.4) | N |
| Juxtacortical (LL) | Mean (SD) | 10(20.7) | 3(3.8) | 16.3(45.8) | N |
| Juxtacortical (NL) | Mean (SD) | 27.6(15.2) | 26.2(20.3) | 31.9(14.3) | N |
| Posterior Fossa (LL) | Mean (SD) | 0.4(0.7) | 0.8(1.6) | 2.8(3.1) | < 0.05(PP vs SP) |
| Posterior Fossa (NL) | Mean (SD) | 2.6(2.6) | 4.3(7.2) | 13.5(10.5) | < 0.008 (PP vs SP) and p < 0.03 (SP vs RR) |
| Optic Nerve | Mean (SD) | 5.4 ± 8.0 | 10.6 ± 47.5 | 9.8 ± 34.6 | N |
| Spinal Cord (LL) | Mean (SD) | 7.1(11.1) | 5.1(9.2) | 14.7(13.8) | N |
| Spinal Cord (NL) | Mean (SD) | 2.3(2.8) | 6.1(17.0) | 6.5(5.8) | N |
| Load Lesion - Total | Mean (SD) | 34.1(44.1) | 21.9(21.8) | 66.8(109) | N |
| Black Holes | Mean (SD) | 4.8(5.9) | 2.7(5.3) | 16.3(14.5) | < 0.02 (SP vs RR) |
| Enhanced Lesions | Mean (SD) | 4.7(8.5) | 0.2(0.7) | 0.8(1.5) | < 0.04 (PP vs RR) |
| EDSS | Mean (SD) | 5.1(1.6) | 3.3(2.1) | 6.8(2.3) | < 0.04 (PP vs RR) and p < 0.0001 (SP vs RR) |
| Disease duration (years) | Mean (SD) | 15.7(14.8) | 17.1(11.4) | 21.2(13.7) | N |
| Age at MRI (years old) | Mean(SD) | 54.6(12.8) | 45.1(13.4) | 53.1(16.4) | N |
Abbreviations: EDSS, Expanded Disability Status Scale; LL, load lesion; N, Not significant; NL, number of lesions; PP, primary progressive; RR, relapsing-remitting; SP, secondary progressive.