. 2023 Feb 21;3(2):100413. doi: 10.1016/j.crmeth.2023.100413

Table 2.

Performance of various deep neural networks models for IC₅₀ prediction using different therapeutic and disease-state representations

Model Name	Therapeutic representation	Disease state representation	Spearman correlation
DrugCell⁵	Morgan fingerprint	genomic	0.80
Paccmann⁶	SMILE language tokenization	transcriptomic	0.88
DeepDSC⁵⁵	Morgan fingerprint	transcriptomic	0.84
CDRScan⁵⁶	molecular fingerprint	genomic	0.84
tCNNs⁵⁷	one-hot encoding	genomic	0.84
GraphDRP³⁴	molecular graph	genomic	0.85
DeepCDR³⁵	molecular graph	genomic and transcriptomic	0.82
AGMI³⁶	molecular graph	genomic and transcriptomic	0.92

Spearman correlations were reported in the papers referenced or in.³⁶