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. 2023 Feb 21;3(2):100413. doi: 10.1016/j.crmeth.2023.100413

Table 3.

AUC values for random forest models predicting the approval of drug-indication pairs using the features listed

Features Average AUC (10-fold CV) STD AUC (10-fold CV)
ORR 0.83 0.13
ORR + predicted toxicity 0.89 0.08
ORR + predicted IC50 0.88 0.07
ORR + predicted toxicity + predicted efficacy 0.89 0.06