REAGENT or RESOURCE	SOURCE	IDENTIFIER
Chemicals, peptides, and recombinant proteins
Erlotinib Hydrochloride EGFR inhibitor	MedChemExpress(MCE)	HY-12008; CAS: 183319-69-9
Gefitinib (ZD1839) EGFR inhibitor	MedChemExpress(MCE)	HY-50895; CAS: 184475-35-2
AZD1775 Wee1 inhibitor	MedChemExpress(MCE)	HY-10993; CAS: 955,365-80-7
MK-5180 Aurora A inhibitor	MedChemExpress(MCE)	HY-13252; CAS: 1010085-13-8
Etoposide Topoisomerase-II inhibitor	MedChemExpress(MCE)	HY-13629; CAS: 33419-42-0
Dinaciclib CDK inhibitor	MedChemExpress(MCE)	HY-10492; CAS: 779353-01-4
Critical commercial assays
Counting Kit-8 (CCK8) assay	Sigma-Aldrich	M5655
Deposited data
DrugComb	Zagidullin et al.41	https://drugcomb.fimm.fi/
DrugCombDB	Liu et al.42	http://drugcombdb.denglab.org/main
AstraZeneca-Sanger Drug Combination Prediction	Menden et al.43	https://www.synapse.org/#!Synapse:syn4231880/wiki/235645
LINCS L1000	Stathias et al. 81	https://lincsproject.org/LINCS/tools/workflows/find-the-best-place-to-obtain-the-lincs-l1000-data
Experimental models: Cell lines
Human:HT29	ATCC	ATCC HTB-38
Software and algorithms
ForSyn	This paper	https://doi.org/10.5281/zenodo.7562405
Original Deep Forest	Zhou et al.31	https://github.com/kingfengji/gcForest
DCE-DForest	Zhang et al.37	N/A
DeepSynergy	Preuer et al.18	www.bioinf.jku.at/software/DeepSynergy
MatchMaker	Kuru et al.19	https://github.com/tastanlab/matchmaker
TranSynergy	Liu et al.22	https://github.com/qiaoliuhub/drug_combination
SynPathy	Tang et al.52	https://github.com/TangYiChing/SynPathy
DeepDDS	Wang et al.23	https://github.com/Sinwang404/DeepDDS/tree/master
ChemmineR	Cao et al.82	https://www.bioconductor.org/packages/release/bioc/html/ChemmineR.html
OpenBabel	O'Boyle et al.83	https://openbabel.org/wiki/Category:Installation