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Cytotoxicity of compounds 1-11
| Compound | IC50 (μmol/L) | |||
|---|---|---|---|---|
| 786-O | SW1990 | SW480 | LO2 | |
| 1 | – | – | 32.6±1.2 | – |
| 2 | – | 33.2±5.1 | – | – |
| 3 | – | 24.7±2.2 | 30.2±4.8 | – |
| 4 | 18.3±1.9 | 19.6±2.8 | – | – |
| 5 | 24.7±1.8 | – | – | – |
| 6 | – | – | – | – |
| 7 | 33.4±1.8 | 30.4±5.1 | 27.2±6.5 | – |
| 8 | – | – | – | – |
| 9 | – | – | – | – |
| 10 | 4.3±0.7 | 14.1±1.8 | 4.9±0.3 | 11.1±2.4 |
| 11 | – | – | – | – |
| Cisplatin | 2.5±0.6 | 33.8±4.7 | 26.7±4.6 | 5.2±0.6 |
All data shown above are mean±SD of three independent experiments. IC50: half maximal inhibitory concentration; SD: standard deviation. "‒": >40 μmol/L.
