Table 1.
Mean age (range) (years) | 71 (40–84) |
---|---|
Sex | |
Male | 156 (34) |
Female | 294 (66) |
Primary site | |
Colon | 272 (60) |
Rectum | 178 (40) |
Initial treatment | |
Surgery | 371 (82) |
RCHT + surgery | 68 (15) |
Systemic therapy | 11 (3) |
Adjuvant chemotherapy | |
Yes | 114 (25) |
No | 324 (72) |
Unknown | 12 (3) |
Histology | |
Adenocarcinoma | 429 (95) |
Mucinous carcinoma | 21 (5) |
Initial stage | |
Stage I | 15 (3) |
Stage II | 94 (21) |
Stage III | 186 (41) |
Stage IV | 127 (28.5) |
Unknown | 28 (6.5) |
Tumor mutations (%) | |
EGFR | 3.3 |
KRAS | 22.6 |
NRAS | 3 |
BRAF | 1.76 |
MSI | 0.44 |
Median time to OMD (range) | 23.7 (0–126) |
Systemic treatment before SABR | |
Chemotherapy | 249 (55.5) |
TKI | 4 (0.9) |
Antiangiogenetic | 32 (7) |
Target therapy/immunotherapy | 6 (1.3) |
No | 118 (26.3) |
Unknown | 41 (9) |
Type of oligometastases | |
Synchronous | 106 (23.5) |
Metachronous | 344 (76.5) |
RCHT: radiochemotherapy; OMD: oligometastatic disease: SBRT: stereotactic body radiotherapy; TKI: tyrosine-kinases inhibitor |