Table 5.

Subgroup Analysis.

	HR [95 % CI]		p-value
Multivariate Analysis Excluding Node Positive or Metastasis
BED3 (Quartiles):
<145	1(ref)
145–180	1.06 [0.62 – 1.82]		0.83
180–225	1.79 [0.99 – 3.26]		0.06
>225	0.73 [0.42 – 1.26]		0.25
Age	1.03 [1.01 – 1.05]		<0.01
Multivariate Analysis Excluding Transitional Cell Histology
BED3 (Quartiles):
<145	1(ref)
145–180	1.12 [0.67 – 1.87]		0.66
180–225	1.84 [1.03 – 3.29]		0.04
>225	0.71 [0.41 – 1.21]		0.21
Age	1.03 [1.01 – 1.05]		<0.01
Clinical T Stage:
cT1a	1(ref)
cT1b	1.56 [1.04 – 2.34]		0.03
cT2 – cT4	1.25 [0.67 – 2.25]		0.52
Clinical M Stage
cM0	1(ref)
cM1	9.32 [3.86 – 22.51]		<0.01