Table 2.

Kidney biopsy findings: summary of light microscopy, immunofluorescence, and electron microscopic findings

Patient No.	Glomeruli: total/sclerosed	Pattern of injury	Thrombi in GC	Mesangiolysis	Double contours	Arteriosclerosis	%IFTA	IF	EM
1	10/2	MPGN	Negative	+	+	2+	30	C3: 2+	Mesangial and capillary wall deposits with humps, subendothelial fluff, double contours
2	17/0	MPGN	Negative	Absent	+	1+	10	C3: 3+; IgM: 1+	Mesangial and capillary wall deposits, subendothelial fluff
3	9/0	MES	Negative	Present	-	1+	20	C3: 2+	Mesangial and capillary wall deposits with humps, subendothelial fluff
4	21/5	MES	Negative	Absent	-	1+	25	C3: 3+	Mesangial deposits and subendothelial fluff, endothelial swelling with capillary lumen compromise, double contours
5	24/9	MPGN/CRES with 40% crescents	Negative	Present	+	2+	10	C3: 3+	Mesangial and capillary wall deposits, subendothelial fluff, endothelial swelling, double contours, fibrin tactoids

CRES, crescentic; EM, electron microscopy; IF, Immunofluorescence; IFTA, interstitial fibrosis and tubular atrophy: grading: minimal (<10%); mild (10%−25%); moderate (26%−50%); severe (>50%), MPGN, membranoproliferative glomerulonephritis pattern of injury; MES, mesangial; SCL, sclerotic