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. Author manuscript; available in PMC: 2023 Nov 1.
Published in final edited form as: Eur J Radiol. 2022 Sep 15;156:110523. doi: 10.1016/j.ejrad.2022.110523

Table 5.

Sensitivity, specificity, PPV, NPV, diagnostic accuracy, and AUC for DCE, DWI using the determined best cut-off for each reader, and each mpMRI reading approach (EUSOBI mpMRI, 1.5 mpMRI, adapted mpMRI, and mpMRI individual threshold) for both readers. Significant differences before adjusting for multiple comparison are indicated.

READER Modality Sensitivity
(95% CI)		 Specificity
(95% CI)		 PPV
(95% CI)		 NPV
(95% CI)		 Accuracy
(95% CI)
Reader 1 DCE 94.82
(82.72–99.44)		 66.66
(45.98–83.38)		 80.52
(66–90.64)		 89.98
(68.2–98.78)		 83.38
(72.16–91.3)
DWI individual best threshold 1.215 74.36
(57.86–86.9)† 		66.66
(45.98–83.38)		 76.34
(59.84–88.66)		 64.24
(44–81.4)		 71.28
(58.74–81.62)
EUSOBI mpMRI 84.7
(69.52–94.16)		 55.66
(35.42–74.58)‡ 		73.26
(58.08–85.36)		 71.5
(47.74–88.66)		 72.82
(60.28–82.94)‡
1.5 mpMRI 87.12
(72.6–95.7)		 29.7
(13.86–50.16)†‡*☩⟐ 		64.24
(49.72–76.78)		 61.6
(31.68–86.24)		 63.58
(50.82–75.24)†
adapted mpMRI 87.12
(72.6–95.7)		 85.14
(66.22–95.92)☩ 		89.54
(75.24–97.02)		 82.06
(63.14–93.94)		 86.46
(50.82–75.24)
mpMRI individual best threshold 1.215 74.36
(57.86–86.9)† 		66.66
(45.98–83.38)		 76.34
(59.84–88.66)		 64.24
(44–81.4)		 71.28
(58.74–81.62)
Reader 2 DCE 100
(..−..)		 77.88
(57.64–91.3)		 86.68
(73.26–95.04)		 100
(..−..)		 90.86
(81.18–96.58)
DWI individual best threshold 1.305 79.42
(63.58–90.64)		 81.4
(61.82–93.72)		 86.02
(70.4–95.26)		 73.26
(54.12–87.78)		 80.3
(68.64–89.1)
EUSOBI mpMRI 77
(60.72–88.88)		 81.4
(61.82–93.72)		 85.8
(69.74–95.26)		 71.06
(51.92–85.8)		 78.76
(66.88–87.78)†
1.5 MRI 94.82
(82.72–99.44)‡*☩⟐ 		40.7
(22.44–61.16)†‡*☩⟐ 		69.74
(55.66–81.62)		 84.7
(54.56–98.12)		 72.82
(60.28–82.94)†
adapted mpMRI 71.72
(55.22–84.92)		 85.14
(66.22–95.92)		 87.56
(71.06–96.58)		 67.54
(49.5–82.72)		 77.22
(65.34–86.68)†
mpMRI individual best threshold 1.305 79.42
(63.58–90.64)		 81.4
(61.82–93.72)		 86.02
(70.4–95.26)		 73.26
(54.12–87.78)		 80.3
(68.64–89.1)
†

Significantly different from DCE-MRI (p < 0.05)

‡

Significantly different from adapted mpMRI (p < 0.05)

*

Significantly different from DWI individual best threshold (p < 0.05)

☩

Significantly different from EUSOBI mpMRI (p < 0.05)

⟐

Significantly different from mpMRI individual best threshold (p < 0.05)