Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Feb 27;25(3):493–507. doi: 10.1038/s41556-023-01093-0

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Extended Data Fig. 4 — a, Scatterplots showing the correlation of expression levels between DAB1 mRNA and the total DAB1 protein, phospho-DAB1 (pSTY), or phospho-DAB1 (Y232) in all MB tumors (n = 45). b, Boxplot showing the levels of phospho-DAB1 (pSTY) protein expression in the MB proteomics dataset (n_G3 = 14_, n_G4 = 13, n_SHH = 13, and n_WNT = 3). c, Violin plot showing DAB1 mRNA expression in four MB subgroups and normal cerebellum. d, Scatterplot showing the correlation between SMARCD3 protein expression levels and the phospho-DAB1 (pSTY) protein levels in all MBs. e, f, Scatterplot showing the correlation between SMARCD3 and DAB1 mRNA expression levels in all cancer types and gliomas using the datasets from the TARGET and TCGA projects. The dashed line outlines the glioblastomas and low-grade gliomas. g, Scatterplot showing the correlations between SMARCD3 mRNA expression levels and DAB1 mRNA expression levels in normal tissues using the datasets from the GTEx projects. h, Scatterplot showing the correlations between SMARCD3 and DAB1 mRNA expression levels in brain tissues only. Dashed line circles highlight the tissues from the cerebellum and cerebellar hemisphere (g, h). i, Percentage of gene expression variance explained by species and by organs. Data from the reference²⁵ were used for analysis, including six organs (brain, cerebellum, heart, kidney, liver, and testis) in seven vertebrate species (chicken, chimpanzee, human, mouse, opossum, platypus, and rhesus). Each color dot represents one tumor sample (a-f), a normal tissue sample (g-h), or a gene (i). The red dot is explained mostly by organ differences, while the blue dot is by species differences (i). P and R values were calculated using two-tailed Welch’s t-test with FDR correction (b) and/or two-tailed Spearman’s rank correlation analysis (a, d, e, f, g, h).