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. 2023 Mar 1;14:1139595. doi: 10.3389/fimmu.2023.1139595
PD-1/PD-L1 programmed cell death protein 1/programmed cell death ligand 1
CAR-T cell chimeric antigen receptor T-cell
DCs dendritic cells
ILCs innate lymphocytes
NK natural killer
PRRs pattern recognition receptors
PAMPs pathogen-associated molecular patterns
DAMPs danger-associated molecular patterns
cGAS cyclic guanosine monophosphate-adenosine monophosphate synthase
dsDNA double-stranded DNA
STING stimulator interferon gene
ER endoplasmic reticulum
cGAMP cyclic guanosine monophosphate-adenosine monophosphate
IFN interferon
APCs antigen-presenting cells
STAT1 signal transducer and activator of transcription 1
EMT epithelial-mesenchymal transition
TME tumor microenvironment
ISG invariant surface glycoprotein
cGAMP-NP cGAMP nanoparticles
MDSCs myeloid derived suppressor cells
IDO indolamine 2,3-dioxygenase
LKB1 liver kinase B1
NSCLC non-small cell lung cancer
CMA chaperone-mediated autophagy
ATG autophagy-related gene
PI3K phosphoinositide 3-kinase
PE phosphatidylethanolamine
PI3KC3 class III PI3K
ROS reactive oxygen species
FoxO Forkhead box O
UBD ubiquitin binding domain
MHC major histocompatibility complex
PDAC pancreatic ductal adenocarcinoma
LAP LC3-associated phagocytosis
TAMs tumor-associated macrophages
Gal-1 galectin-1
HCC Hepatocellular carcinoma
LIRs LC3-interacting regions
TRIM14 triplet motif containing 14
ERGIC ER–Golgi intermediate compartment
UPR unfolded protein response
PERK PKR-like ER kinase
TGN trans-Golgi network