PD-1/PD-L1 |
programmed cell death protein 1/programmed cell death ligand 1 |
CAR-T cell |
chimeric antigen receptor T-cell |
DCs |
dendritic cells |
ILCs |
innate lymphocytes |
NK |
natural killer |
PRRs |
pattern recognition receptors |
PAMPs |
pathogen-associated molecular patterns |
DAMPs |
danger-associated molecular patterns |
cGAS |
cyclic guanosine monophosphate-adenosine monophosphate synthase |
dsDNA |
double-stranded DNA |
STING |
stimulator interferon gene |
ER |
endoplasmic reticulum |
cGAMP |
cyclic guanosine monophosphate-adenosine monophosphate |
IFN |
interferon |
APCs |
antigen-presenting cells |
STAT1 |
signal transducer and activator of transcription 1 |
EMT |
epithelial-mesenchymal transition |
TME |
tumor microenvironment |
ISG |
invariant surface glycoprotein |
cGAMP-NP |
cGAMP nanoparticles |
MDSCs |
myeloid derived suppressor cells |
IDO |
indolamine 2,3-dioxygenase |
LKB1 |
liver kinase B1 |
NSCLC |
non-small cell lung cancer |
CMA |
chaperone-mediated autophagy |
ATG |
autophagy-related gene |
PI3K |
phosphoinositide 3-kinase |
PE |
phosphatidylethanolamine |
PI3KC3 |
class III PI3K |
ROS |
reactive oxygen species |
FoxO |
Forkhead box O |
UBD |
ubiquitin binding domain |
MHC |
major histocompatibility complex |
PDAC |
pancreatic ductal adenocarcinoma |
LAP |
LC3-associated phagocytosis |
TAMs |
tumor-associated macrophages |
Gal-1 |
galectin-1 |
HCC |
Hepatocellular carcinoma |
LIRs |
LC3-interacting regions |
TRIM14 |
triplet motif containing 14 |
ERGIC |
ER–Golgi intermediate compartment |
UPR |
unfolded protein response |
PERK |
PKR-like ER kinase |
TGN |
trans-Golgi network |