Table 2.
Demographic characteristics, baseline and follow-up evaluation, workflow times and outcome in patients after first matching step
| IVT and MT overlap | IVT before MT over 50 min | p | |
|---|---|---|---|
| Demographic characteristics | |||
| Age (years) |
76 IQR 67-82 (n = 209) |
76 IQR 67-82 (n = 209) |
0.963 |
| Sex, female No./total (%) | 108/209 (51.7) | 108/209 (51.7) | 1 |
| Clinical and imaging evaluation at presentation | |||
| Baseline pmRS |
0 IQR 0-1 (n = 203) |
0 IQR 0-1 (n = 207) |
0.300 |
| Baseline NIHSS Admission |
14 IQR 9-18 (n = 207) |
14 IQR 9-18 (n = 207) |
1 |
| Baseline ASPECTS |
9 IQR 8-10 (n = 189) |
9 IQR 8-10 (n = 184) |
0.868 |
| Workflow times | |||
| Time from SO to IVT |
120 IQR 90-155 (n = 203) |
70 IQR 55-85 (n = 202) |
<0.001 |
| Time from SO to FLR |
199 IQR 163-236 (n = 195) |
198 IQR 170-238 (n = 181) |
0.708 |
| Time from SO to GRO |
149 IQR 125-184 (n = 209) |
152 IQR 127-180 (n = 209) |
0.628 |
| Clinical and imaging evaluation after intervention | |||
| Treat ae ICH | 8 (3.8%) (n = 209) | 7 (3.3%) (n = 209) | 1.0 |
| 24h NIHSS |
7 IQR 2-15 (n = 189) MW 9.9 ± 9.4 |
8 IQR 3-16 (n = 194) MW 10.3 ± 8.6 |
0.384 |
| BL-24 h NIHSS |
4 IQR 0-9 (n = 188) |
3 IQR 0-8 (n = 193) |
0.118 |
| 24h NIHSS (0.1) | 32/209 (15.3%) | 32/209 (15.3%) | – |
| 24h mRS |
4 IQR 2-5 (n = 190) MW 3.6 ± 1.6 |
4 IQR 2-5 (n = 197) MW 3.6 ± 1.6 |
0.950 |
| Functional long-term outcome | |||
| D90 mRS |
3 IQR 1-5 (n = 184) MW 2.8 ± 2.2 |
3 IQR 1-6 (n = 192) MW 3.2 ± 2.2 |
0.052 |
| Death | 29/184 (15.8%) | 51/192 (26.6%) | 0.013 |
| Procedural outcome | |||
| Treat final TICI |
3 (n = 207) |
2b (n = 204) |
0.026 |
| 0 |
2.6% (n = 6) |
5.9% (n = 12) |
– |
| 1 |
2.4% (n = 5) |
0.9% (n = 2) |
– |
| 2a |
4.3% (n = 9) |
6.4% (n = 13) |
– |
| 2b |
32.4% (n = 67) |
39.7% (n = 81) |
– |
| 3 |
57.9% (n = 120) |
47.0% (n = 96) |
– |
24h mRS Modified Rankin Scale after 24 hours, BL-24 h NIHSS baseline NIHSS-NIHSS after 24 hours, 24h NIHSS (0.1) NIHSS of 0 or 1 after 24 hours, ACA Anterior cerebral artery, ASPECTS Alberta Stroke Program Early CT Score, D90 mRS Modified Rankin Scale after 90 days, FLR flow restoration, GRO groin puncture, IVT Intravenous thrombolysis, MCA Middle cerebral artery, NIHSS National Institutes of Health Stroke Scale, PCA Posterior cerebral artery, pmRS pretreatment modified Rankin Scale, SO symptom onset, TICI Thrombolysis in cerebral infarction, Treat ae ICH post treatment intracranial hemorrhage, Treat final TICI TICI after treatment