Table 3.
Demographic characteristics, baseline and follow up evaluation, workflow times and outcome in patients after second matching step
| IVT and MT overlap | IVT before MT over 50 min | p | |
|---|---|---|---|
| Demographic characteristics | |||
| Age (years) |
76 IQR 68-82 (n = 149) |
77 IQR 68-82 (n = 149) |
0.685 |
| Sex, female No./total (%) | 82/149 (55) | 82/149 (55) | 1 |
| Clinical and imaging evaluation at presentation | |||
| Baseline pmRS |
0 IQR 0-1 (n = 143) |
0 IQR 0-1 (n = 147) |
0.364 |
| Baseline NIHSS Admission |
14 IQR 9-17 (n = 148) |
14 IQR 9-17 (n = 148) |
1 |
| Baseline ASPECTS |
9 IQR 8-10 (n = 134) |
9 IQR 8-10 (n = 132) |
0.495 |
| Workflow times | |||
| Time from SO to IVT |
120 IQR 90-152 (n = 145) |
70 IQR 55-90 (n = 144) |
<0.001 |
| Time from SO to FLR |
203 IQR 164-244 (n = 135) |
201 IQR 177-244 (n = 131) |
0.579 |
| Time from SO to GRO |
154 IQR 128-187 (n = 149) |
155 IQR 127-184 (n = 149) |
0.957 |
| Clinical and imaging evaluation after intervention | |||
| Treat ae ICH | 6 (4%) (n = 149) | 6 (4%) (n = 149) | – |
| 24h NIHSS |
8 IQR 2-16 (n = 131) MW 10.7 ± 10.2 |
8 IQR 4-18 (n = 137) MW 10.4 ± 8.5 |
0.733 |
| BL-24 h NIHSS |
4 IQR 0-7 (n = 131) |
4 IQR −1-8 (n = 136) |
0.834 |
| 24h NIHSS (0.1) | 23/131 (17.5%) | 22/137 (16.1%) | – |
| 24h mRS |
4 IQR 2-5 (n = 133) MW 3.6 ± 1.6 |
4 IQR 2-5 (n = 140) MW 3.6 ± 1.6 |
0.648 |
| Functional long-term outcome | |||
| D90 mRS |
3 IQR 1-5 (n = 132) MW 2.9 ± 2.2 |
3 IQR 1-6 (n = 140) MW 3.4 ± 2.3 |
0.090 |
| Death | 25/132 (18.9%) | 43/140 (30.7%) | 0.006 |
| Procedural outcome | |||
| Treat final TICI |
3 (n = 148) |
2b (n = 147) |
0.238 |
| 0 |
3.3% (n = 5) |
6.8% (n = 10) |
– |
| 1 |
3.3% (n = 5) |
0.6% (n = 1) |
– |
| 2a |
6.1% (n = 9) |
6.8% (n = 10) |
– |
| 2b |
34.5% (n = 51) |
39.5% (n = 58) |
– |
| 3 |
52.7% (n = 78) |
46.3% (n = 68) |
– |
24h mRS Modified Rankin Scale after 24 hours, BL-24 h NIHSS baseline NIHSS- NIHSS after 24 hours, 24h NIHSS (0.1) NIHSS of 0 or 1 after 24 hours, ACA Anterior cerebral artery, ASPECTS Alberta Stroke Program Early CT Score, D90 mRS Modified Rankin Scale after 90 days, FLR flow restoration, GRO groin puncture, IVT Intravenous thrombolysis, MCA Middle cerebral artery, NIHSS National Institutes of Health Stroke Scale, PCA Posterior cerebral artery, pmRS pretreatment modified Rankin Scale, SO symptom onset, TICI Thrombolysis in cerebral infarction, Treat ae ICH post treatment intracranial hemorrhage, Treat final TICI TICI after treatment