FIGURE 2.

Routine US and SHAPE US Examination of AS Plaque. (a) Routine ultrasonography of carotid artery with AS plaque, the white arrow indicates an isoechoic plaque; (b) CEUS of carotid artery with AS plaque, the white arrow indicates that the plaque can be clearly displayed in subharmonic mode. (c) The point (the intersection of red and yellow lines in the growth phase) was selected as the optimum MI; (d) ROIs with 1 mm sampling frame were selected in the upstream shoulder, downstream shoulder, top section of atherosclerotic plaques, and the above three corresponding horizontal lumens of the plaque. AS, atherosclerosis; CEUS, contrast‐enhanced ultrasound; MI, mechanical index; ROI, region of interest; US, ultrasound.