Table 2.
Clinical and radiological outcome of patients with unknown onset and unknown time last known well (LKWu) undergoing endovascular therapy compared to patients with known onset (KO) and to patients with unknown onset but known last known well (LKWk)
| LKWu | KO | LKWk | |
|---|---|---|---|
| 24 h follow-up | |||
| NIHSS, median (Q1–Q3) | 14 (6–21) | 9 (3–18)a | 12 (5–20)a |
| Any intracranial hemorrhage, n (%) | 67 (11.9) | 389 (11.1) | 223 (12.1) |
| Symptomatic intracranial hemorrhage, n (%) | 29 (5.2) | 116 (3.3) | 67 (3.6) |
| Discharge follow-up | |||
| NIHSS, median (Q1–Q3) | 8 (2–16) | 4 (1–12)a | 7 (3–15) |
| Length of stay, days, median (Q1–Q3) | 10 (6–15) | 8 (5–13)a | 9 (6–14) |
| Death, n (%) | 103 (18.8) | 517 (15.0) | 319 (17.5) |
| 90 days follow-up | |||
| Functional independency (mRS ≤ 2), n (%) | 126 (27.0) | 1297 (42.6) | 514 (31.8) |
| mRS, median (Q1–Q3) | 4 (2–6) | 3 (1–6)a | 4 (2–6) |
| Death, n (%) | 149 (32.0) | 777 (25.5) | 524 (32.4) |
LKWu time last known well unknown, KO known onset, LWKk time last known well known, NIHSS National Institutes of Health Stroke Scale, mRS modified Rankin scale
aIndicates a significant difference compared to LKWu patients (p < 0.05 in multivariable regression adjusted for age, sex, premorbid mRS, NIHSS at admission, initial Alberta Stroke Programme Early Computed Tomography Score, intravenous thrombolysis, time admission-flow restoration, successful recanalization)