TABLE 5.
Partial signal transduction differential genes.
| Gene-id | Gene name | Gene function | Up/Down LC vs. HC |
|---|---|---|---|
| CL1Contig15487 | BMP4 | bone morphogenetic protein 4 | Down |
| CL1Contig18178 | SIAH1 | E3 ubiquitin-protein ligase SIAH1 | Up |
| CL6915Contig1 | MAPK1_3 | mitogen-activated protein kinase 1/3 | Up |
| comp10606_c0_seq1_2 | XPO1 | exportin-1 | Up |
| CL13099Contig1 | ndk, NME | nucleoside-diphosphate kinase | Down |
| CL16049Contig1 | ADIPOR | adiponectin receptor | Up |
| CL1Contig20063 | RAPTOR | regulatory associated protein of mTOR | Up |
| CL1Contig20760 | SCD | stearoyl-CoA desaturase (Delta-9 desaturase) | Up |
| CL1Contig9488 | MDM2 | E3 ubiquitin-protein ligase Mdm2 | Up |
| comp77726_c0_seq4_3 | BRCA1 | breast cancer type 1 protein | Up |
| CL1Contig13091 | EX | protein expanded | Up |
| CL1Contig791 | MOB1 | MOB kinase activator 1 | Up |
| CL11393Contig1 | PIK3C2 | phosphatidylinositol-4-phosphate 3-kinase | Up |
| CL1Contig16972 | ABL1 | abelson tyrosine-protein kinase 1 | Up |
| comp26341_c0_seq1_2 | MCU | calcium uniporter protein, mitochondrial | Up |
| CL1Contig12468 | PPP1R12A | protein phosphatase 1 regulatory subunit 12A | Up |
| comp3209_c1_seq1_2 | KCNMA1 | calcium-activated channel subfamily M alpha member 1 | Down |
| CL15441Contig1 | ARF1 | ADP-ribosylation factor 1 | Down |
| CL1Contig2700 | CIC | capicua transcriptional repressor | Up |
| CL13825Contig1 | YWHAE | 14-3-3 protein epsilon | Down |
| comp41280_c0_seq1_2 | RPS6 | small subunit ribosomal protein S6e | Down |
| CL2913Contig1 | ACTB_G1 | actin beta/gamma 1 | Up |
| CL15002Contig1 | CAMK2 | calcium/calmodulin-dependent protein kinase (CaM kinase) II | Down |
| CL14773Contig1 | SLC25 | solute carrier family 25 | Down |