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. Author manuscript; available in PMC: 2024 Mar 1.
Published in final edited form as: J Surg Res. 2022 Dec 15;283:1106–1116. doi: 10.1016/j.jss.2022.11.048

Figure 1.

Figure 1.

Relative gene expression of occludin and claudin-1 normalized to GAPDH in control vs untreated NEC derived enteroids, *p=0.04 for occludin, **p=0.006 for claudin-1, n=3 in each treatment group (A). Expression of the protein occludin relative to control and normalized to GAPDH in control vs NEC derived enteroids, **p=0.003, n=3 in the control group, n=2 in the NEC group (B). Representative western blot of occludin, claudin-1 and GAPDH in control vs NEC derived enteroids, n=3 in the control group, n=2 in the NEC group (C). Expression of the protein claudin-1 relative to control and normalized to GAPDH in control vs NEC derived enteroids, *p=0.01, n=3 in the control group, n=2 in the NEC group (D). Relative gene expression of ki-67, TNF-α and IL-8 normalized to GAPDH in control vs untreated NEC derived enteroids, *p=0.04 for ki-67, p=0.42 for TNF-α and IL-8, n=3 for each treatment group (E). Concentration of TNF-α in the media of untreated control vs NEC derived enteroids, p=0.60, n=3 in each group (F).