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. 2023 Mar 15;14(3):197. doi: 10.1038/s41419-023-05722-2

Fig. 4. SRY represses TSPYL2 accumulation in male cancer cells after DNA damage.

Fig. 4

A Agarose gel electrophoresis of SRY RT-PCR products derived from untreated and etoposide-treated control and SRY silenced MG-63 cells. Signals represent negative printing of ethidium bromide staining. B Western blot analysis of TSPYL2 induction at 24 h and 48 h after etoposide treatment in SRY-depleted MG-63. C Western blot analysis of TSPYL2 induction at 24 h and 48 h after etoposide treatment in ARPE-19, U2OS and HeLa cells transfected with MOCK or SRY expression vector. D Western blot analysis of MDM2 levels at 24 h and 48 h after etoposide treatment in SRY-depleted MG-63 cells.