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Genotoxic agents and their action.
| DRUG | ACTIVITY |
|---|---|
| Etoposide (Eto) | Topoisomerase II inhibitor |
| Neocarzinostatin (NCS) | Radiomimetic drug |
| UV | Pyrimidine dimers formation |
| Gemcitabine (Gem) | DNA synthesis inhibitor |
| Hydroxyurea (HU) | Ribonucleotide reductase inhibitor |
| Camptothecin (CPT) | Topoisomerase I inhibitor |
| Nocodazole (Noco) | Microtubules depolarization |
Genotoxic agents tested in these experiments and their action are reported in the table.
