Figure 1.

Patients under 65 and over 65 years of age differ in hematologic values that predict outcomes. A. Alluvial plots for hematological cell populations in patients under 65 or over 65. No apparent relation between hematological parameters and outcomes is recorded at admission, while after 7 days, case clusters are obvious for some conditions. In elderly, higher WBC counts and NLR, low levels of lymphocytes and monocytes, and high levels of neutrophils and eosinophils relates to poor or fatal outcomes. Meanwhile, survivors are more frequent at younger ages, concomitant to low WBC and NLR and high numbers of lymphocytes. B. Alluvial plots for inflammatory markers expression at admission and followed by 7 days in survivors and deceased patients. Prediction of outcomes according to inflammatory parameters is clearer in middle age than in older adults. Low values of LDH, CRP and D–dimer are associated with better outcomes. Reference values: white blood cells (WBC): 4–11×10³ cells/µL, neutrophil/lymphocyte ratio (NLR): 1–3, Lymphocytes: 17–45%, Monocytes: 2–12%, Neutrophils: 37–75%, Eosinophils: 1–7%, Basophils: 0.3–2%, Erythrocytes: 4–5×10⁶ cells/µL, Hematocrit: 35–52%, Platelets: 130–400×10³ cells/µL, lactate dehydrogenase (LDH): 240–480 U/L, C–reactive protein (CRP): 0–5 mg/L, D–dimer: 0–500 U/L, Fibrinogen: 308–613 mg/dL, Bilirubin: 1–1.2 mg/dL, Creatinine: 0.7–1.2 mg/dL. ND, no data.