IRCT20201222049802N3.

Study name	Comparative study of the effect of dexamethasone and injectable hydrocortisone in reducing the need for oxygen in preterm infants
Methods	Double‐blind randomized controlled trial
Participants	Fetal age less than 33 weeks, the risk of bronchopulmonary dysplasia more than 60% according to the National Institute of Child Health and Human Development (NICHD) definition, parental consent, having received antenatal corticosteroid
Interventions	Dexamethasone group: Infants of the dexamethasone group will receive dexamethasone injection from day 14 of birth (0.2 mg per kg body weight for the first 3 days and 0.1 mg per kg body weight for the next 4 days). Hydrocortisone group: Infants of the hydrocortisone group will receive hydrocortisone injection from the 14th day of birth (1 mg per kg of body weight for 7 days).
Outcomes	Oxygen saturation. Time point: day 28 after birth. Method of measurement: pulse oximeter.
Starting date	2021‐09‐22
Contact information	Asghar Marzban Address: Ayatollah Mousavi Hospital, Gavazang Road, Above Shahid Sabouti Boulevard, Zanjan, Iran. 4513956183 Telephone: +98 24 3342 0651 Email: Drmarzban@zums.ac.ir Affiliation: Zanjan University of Medical Sciences
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