Differences in self-reported same night sleep quality (A), same day pain (B), and same day depression symptoms (C) in cannabis use days (darker colors) and nonuse days (lighter colors) in the medical cannabis card (MCC) group. Values shown for all MCC participants (N = 102; grey) and those whose presenting problem was mood (depression or anxiety symptoms, Af: n = 44, red), challenges with sleep (In: n = 22, orange), or pain (Pa: n = 36, blue). Data are z scored (standard deviation units) to support effect size interpretation. Displayed values are estimated marginal means and their standard errors from linear mixed effects models fit in primary analyses (covariates include per-participant estimates of age, years of education, and the proportion of daily diary days that included cannabis use [i.e., between-person effect]); see Methods for more detail on parameterization).