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. 2023 Feb 28;6:e40937. doi: 10.2196/40937

Table 1.

Aims and characteristics of the studies.

Study Study type Study aim
Bagnall [46], 2014 Long-term follow-up of RCTa (doctoral dissertation)
  1. To collect 16-month follow-up data of postnatal women who participated in a feasibility RCT investigating an internet-based BAb [42]

  2. To investigate intervention efficacy at a 16-month follow-up

  3. To investigate the intervention adherence and predictors of intervention outcomes

  4. To investigate the predictive role of psychological or demographic factors of attrition throughout the study and at follow-up

Obikane et al [43], 2021 Protocol for RCT
  1. To investigate the efficacy of a postnatal internet-based BA program targeting postpartum depression in reducing depression symptoms (primary aim) as well as mother-child bonding, parental stress, and quality of life

  2. To investigate the program’s efficacy in preventing child psychological and physical abuse and to evaluating the associated child developmental measures

  3. To investigate the program’s acceptability, feasibility, and appropriateness and their association with the participants’ medical and social characteristics

O’Mahen et al [41], 2014 RCT
  1. To investigate the feasibility (primary aim), assessed as treatment adherence, of an internet-based BA program targeting postpartum depression

  2. To investigate the program’s efficacy in reducing depression symptoms compared with usual care

O’Mahen et al [42], 2014 RCT
  1. To investigate the feasibility, assessed as treatment adherence, and to identify adherence predictors (primary aims) of an internet-based BA program targeting postpartum depression

  2. To investigate the program’s efficacy in reducing depression and anxiety symptoms as well as functional impairment, perceived support, and mother-child bonding

O’Mahen et al [45], 2017 Secondary analysis from the study by O’Mahen et al [42]
  1. To investigate the participants’ processes referred to sudden gains and depression spikes associated with an internet-based BA program targeting postpartum depression [42]

  2. To investigate the association between participants’ sudden gains and therapists’ actions

Singla et al [44], 2021 Protocol for 4-arm RCT (noninferiority trial)
  1. To investigate if a BA intervention targeting postpartum depression can be delivered by nonspecialists (primary aim)

  2. To compare the efficacy of a BA intervention in reducing depression symptoms delivered through telemedicine versus delivered in person (primary aim)

  3. To investigate the efficacy of the BA intervention in reducing anxiety symptoms

  4. To investigate the comparative effectiveness of the BA intervention delivered antenatally versus postnatally

  5. To investigate whether the timing of the BA intervention administration differently influences the child’s mental development

  6. To investigate barriers, facilitators, and processes subsuming the BA intervention efficacy in reducing depression and anxiety symptoms

Singla et al [47], 2022 Qualitative study
  1. To qualitatively investigate the barriers and facilitators of BA intervention delivered through telemedicine from both participants’ and intervention providers’ perspectives (ongoing trial)

aRCT: randomized controlled trial.

bBA: behavioral activation.