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. 2023 Feb 16;42(6):e112202. doi: 10.15252/embj.2022112202

Figure EV4. Intestinal inflammation induces distinct transcriptional programs in primary visceral adipocytes.

Figure EV4

  1. Principal component analysis of all mice revealing a strong sex effect in the overall transcriptome.
  2. Differential gene expression assessing transcriptional changes associated with DSS‐induced inflammation after regressing effect of sex and genotypes in visceral adipocytes.
  3. Pathway enrichment analysis of significantly differentially expressed genes in visceral adipocytes during DSS colitis.
  4. Heatmap representing differentially expressed genes associated in fatty acid metabolism during DSS‐induced colitis in visceral adipocytes.
  5. Heatmap representing differentially expressed genes associated with macroautophagy during DSS‐induced colitis in visceral adipocytes.
  6. Normalized counts of Atg8 homologs in visceral adipocytes (n = 12/group).

Data are represented as mean ± s.e.m. (F) Unpaired Student's t‐test. *P < 0.05, ***P < 0.001

Source data are available online for this figure.