Table 1.
Index single nucleotide polymorphisms (SNPs) resulting from a genome-wide analysis of gene-citrus consumption interaction on melanoma risk.
| SNP ID | Chr | Position | Region | Associated gene | Minor allele | MAF | Info score | p-2DF | p-1DF |
|---|---|---|---|---|---|---|---|---|---|
|
| |||||||||
| rs183783391 | 3 | 69950451 | 3p13 | MITF | T | 0.013 | 0.95 | 4.25e-08 | 0.73 |
| rs869329 | 9 | 21804693 | 9p21.3 | MTAP | A | 0.48 | 0.99 | 1.98e-10 | 0.24 |
| rs11446223 | 16 | 90022484 | 16q24.3 | DEF8 | GA | 0.17 | 0.99 | 4.93e-13 | 0.12 |
Abbreviations: Chr, chromosome; Ref allele, reference allele; MAF, minor allele frequency; Info score, imputation quality score; p-1DF, p-value for the conventional 1 degree-of-freedom test; p-2DF, p-value for the 2 degree-of-freedom joint test