Table 3. Droplet Size, Polydispersity Index (PDI), and Zeta Potential of Blank and Loaded (Italics) SEDDS after Emulsification to 1% (v/v) with 25 mM HEPES pH 6.8. Indicated Values Are Means (n ≥ 3) ± SD.
| F | Droplet size [nm] after 0 / 4 h | PDI after 0 / 4 h | Zeta potential [mV] after 0 / 4 h |
|---|---|---|---|
| 1 | 76.5 ± 4.1 / 73.8 ± 2.9 | 0.23 ± 0.01 / 0.24 ± 0.01 | –5.2 ± 0.8 / –5.4 ± 0.9 |
| 122.1 ± 5.6 / 115.1 ± 6.4 | 0.33 ± 0.01 / 0.33 ± 0.02 | –7.4 ± 0.8 / –5.2 ± 1.1 | |
| 2 | 68.3 ± 1.1 / 66.8 ± 0.9 | 0.15 ± 0.01 / 0.14 ± 0.03 | –4.3 ± 0.8 / –5.5 ± 1.2 |
| 81.8 ± 10.6 / 78.1 ± 8.9 | 0.17 ± 0.04 / 0.16 ± 0.03 | –8.3 ± 1.6 / –5.8 ± 1.8 | |
| 3 | 122.1 ± 2.2 / 119.6 ± 2.4 | 0.14 ± 0.01 / 0.13 ± 0.02 | –2.7 ± 0.5 / –4.0 ± 0.6 |
| 129.7 ± 5.6 / 131.5 ± 1.8 | 0.26 ± 0.02 / 0.31 ± 0.01 | –8.8 ± 0.5 / –5.5 ± 1.8 |