Table 2.
Changes in HbA1C (n=10,374) and BMI (n=55,627) Before and During/After Intervention
| Characteristics | No interventiona |
Metformin | LCP:c 1 Session |
LCP: 2–5 sessions |
LCP: ≥6 sessions |
Bariatric surgery |
Metformin and LCP |
Bariatric surgery and metformin |
|---|---|---|---|---|---|---|---|---|
| Full studysample (n) | 63,283 | 2,681 | 1,482 | 950 | 543 | 250 | 203 | 42 |
| Consistent patients for HbA1c analysis (n)b | 8,144 | 719 | 567 | 428 | 287 | 99 | 103 | 27 |
| Number of HbA1c results per patient (baseline) | 1.3 | 1.9 | 1.9 | 2.1 | 2.3 | 2.0 | 2.1 | 1.9 |
| Number of HbA1c results per patient (follow-up) | 1.4 | 1.9 | 2.2 | 2.1 | 1.9 | 1.8 | 1.9 | 1.8 |
| Rounded mean of HbA1c % results (baseline) | 5.70 | 5.90 | 5.79 | 5.81 | 5.85 | 5.75 | 5.90 | 5.87 |
| Rounded mean of HbA1c % results (follow-up) | 5.78 | 5.83 | 5.81 | 5.81 | 5.81 | 5.44 | 5.91 | 5.45 |
| Change in mean HbA1c % | 0.081 | −0.067 | 0.019 | 0.002 | −0.042 | −0.318 | 0.009 | −0.412 |
| Consistent patients for BMI analysis (n)b | 50,530 | 1,878 | 1,335 | 897 | 530 | 240 | 176 | 41 |
| Number of BMI values per patient (baseline) | 6.5 | 11.2 | 14.9 | 16.4 | 16.9 | 29.0 | 13.4 | 18.8 |
| Number of BMI values per patient (follow-up) | 8.2 | 8.0 | 15.2 | 16.4 | 13.8 | 19.1 | 13.3 | 25.8 |
| Rounded mean of BMI kg/m2 values (baseline) | 32.4 | 36.3 | 34.4 | 36.3 | 37.0 | 46.6 | 38.4 | 47.4 |
| Rounded mean of BMI kg/m2 values (follow-up) | 32.9 | 36.5 | 34.6 | 36.8 | 38.0 | 38.6 | 38.9 | 45.0 |
| Change in mean BMI kg/m2 | 0.415 | 0.204 | 0.132 | 0.431 | 0.981 | −8.073 | 0.435 | −2.374 |
Note: Boldface indicates statistical significance (p<0.001) using paired t-tests comparing baseline with follow-up means for each group.
LCP, lifestyle change program.
a
For the no-intervention group, the baseline is a person’s first one-third days, and follow-up is the last one-third days of the study.
b
Patient had at least 1 value before and after intervention.