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. 1985 Jan;44(1):39–44. doi: 10.1136/ard.44.1.39

HLA-DR4 in ankylosing spondylitis with different patterns of joint involvement.

W Miehle, M Schattenkirchner, D Albert, M Bunge
PMCID: PMC1001565  PMID: 3871603

Abstract

Fifty patients with ankylosing spondylitis (AS) confined to the spine and sacroiliac joints were compared with 50 cases of AS complicated by various patterns of non-axial joint involvement. Radiological and clinical features were evaluated and HLA-DR4 typing was carried out. This antigen was found in 16% of 200 normal individuals in 18% of patients suffering from exclusively axial AS, and in 54% of patients with additional purely peripheral joint involvement (wrist, finger, ankle, toe). The possibility that HLA-DR4 represents a non-specific marker for peripheral arthritis in patients with ankylosing spondylitis is discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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