Table 4.
Internalizing Outcomes Assessed (Literature Search 1)
| Internalizing Outcomes | N (%) |
|---|---|
| Animal Studies | |
| Elevated Plus Maze | 10 (37) |
| Open Field | 10 (37) |
| Forced Swim | 9 (33) |
| Running Wheel - Voluntary Activity | 4 (15) |
| Tail Suspension Test | 4 (15) |
| Light Dark Box | 3 (11) |
| Marble Burying Test | 2 (7) |
| Elevated Zero Maze | 1 (4) |
| Hole Board Test | 1 (4) |
| Novelty Suppression Feed Test | 1 (4) |
| Sucrose Preference Test | 1 (4) |
| Cricket predation test | 1 (4) |
| Grooming behaviors | 1 (4) |
| Human Studies | |
| Center for Epidemiologic Studies Depression Scale (CES-D) | 18 (21) |
| Emergency Department Visits | 8 (10) |
| Hospital admissions for depression | 8 (10) |
| Patient Health Questionnaire-9 (PHQ9) | 6 (7) |
| Geriatric Depression Scale (GDS) | 5 (6) |
| SCL-90 | 5 (6) |
| CBCL Anxious/Depressed | 4 (5) |
| Hospital Anxiety and Depression Scale (HADS) | 4 (5) |
| Behavior Assessment System for Children - 2 (BASC2) | 3 (4) |
| Doctor Diagnosis of Major Depressive Disorder | 3 (4) |
| Use of anti-depressant medication | 3 (4) |
| 28-item Inventory of Depression Symptomatology (IDS) | 2 (2) |
| Children’s Depression Inventory (CDI) | 2 (2) |
| Diagnostic Interview Schedule | 2 (2) |
| Edinburg Postnatal Depression Scale (EPDS) | 2 (2) |
| Hospital admissions for anxiety | 2 (2) |
| Insurance claims for depression using ICD-9, ICD-10 codes | 2 (2) |
| Kessler Psychological Distress Scale (K6) | 2 (2) |
| Presence or absence of depressiveness (such as a feeling of sadness or hopelessness lasting more than 2 consecutive weeks) | 2 (2) |
| Self-reported history of depression disorders | 2 (2) |
| Semi-structured Composite International Diagnostic Interview (SCID) | 2 (2) |
| Spence Children’s Anxiety Scale (SCAS) | 2 (2) |
| Suicide attempts | 2 (2) |
| Medical Symptoms Questionnaire (MSQ) | 1 (1) |
| Crown Crisp Phobic Anxiety Scale | 1 (1) |
| Deficient Emotional Self-Regulation (DESR) | 1 (1) |
| Mini International Neuropsychiatric Interview (MINI) | 1 (1) |
| “Have you ever felt sadness or despair in the last two consecutive weeks in the recent year”? | 1 (1) |
| Use of anxiety medication | 1 (1) |
| Self-reported history of anxiety disorders | 1 (1) |
| Hedonic Unhappiness | 1 (1) |
| ICPC codes for Depression or Anxiety | 1 (1) |
| Depression Screener for Teenagers (DesTeen) | 1 (1) |
| Beck Anxiety Inventory (BAI) | 1 (1) |
| Multidimensional Anxiety Scale Children (MASC) | 1 (1) |
| 40-item four dimensional symptom questionnaire (4DSQ) | 1 (1) |
| Beck Depression Inventory (BDI) | 1 (1) |
| Strength and Difficulties Questionnaire (SDQ) | 1 (1) |
| Insurance claims for anxiety using ICD-9, ICD-10 codes | 1 (1) |
| Cause of death was suicide (ICD-10 codes) | 1 (1) |
| Frequency of depressed emotions in recent months | 1 (1) |
| K10-distress | 1 (1) |
| University of Wales Institute of Science and Technology (UWIST) Mood Adjective Check List (MACL) | 1 (1) |
| Generalized Anxiety Disorder (GAD-7) scale | 1 (1) |
| General Health Questionnaire (GHQ-12) | 1 (1) |
| Composite International Diagnostic Interview (CIDI) | 1 (1) |
| Structured clinical interview (DSM-IV) | 1 (1) |
| “Has a doctor diagnosed or treated you for depression during the last year (12 months)?” | 1 (1) |
| State-Trait Anxiety Inventory (STAI) | 1 (1) |
| Outpatient anxiety visits | 1 (1) |
| Outpatient depression visit | 1 (1) |
| SF-36 | 1 (1) |
| Search words related to anxiety | 1 (1) |