Table 3.
Diagnostic Accuracy of the Coding Algorithms Developed to Identify Patients with Crohn’s Disease in the Cohort of Biological Drug Users from Caserta LHU in the Years 2015–2018
| Algorithms | Sensitivity (95% CI) | Specificity (95% CI) | Positive Predictive Value (95% CI) | Negative Predictive Value (95% CI) | F-score | Youden Index | N of Identified CD Cases/Users of Biological Drugs Approved for IBDs (%) |
|---|---|---|---|---|---|---|---|
| 1 | 91.6 (83.4–96.5) | 98.1(96.6–99.1) | 88.4(80.4–93.4) | 98.7(97.4–99.4) | 0.89 | 0.897 | 116/1205 (9.6) |
| 2 | 91.6(83.4–96.5) | 97.8(96.1–98.8) | 86.4(78.3–91.7) | 98.7(97.4–99.3) | 0.87 | 0.894 | 119/1205 (9.9) |
| 3 | 98.8(93.5–100.0) | 97.2(95.5–98.4) | 84.5(76.8–90.1) | 99.8(98.7–100.0) | 0.87 | 0.960 | 132/1205 (10.9) |
| 4 | 71.1(60.1–80.5) | 97.9(96.4–98.9) | 84.3(74.6–90.7) | 95.7(94.0–96.9) | 0.81 | 0.690 | 96/1205 (7.9) |
| 5 | 96.4(89.8–99.2) | 97.8(96.1–98.8) | 86.9(79.2–92.1) | 99.4(98.3–99.8) | 0.88 | 0.942 | 127/1205 (10.5) |
Abbreviations: CD, Crohn’s disease; CI, confidence interval; ETP, electronic therapeutic plan; IBDs, inflammatory bowel diseases.