TABLE 1:

Brain MRI Protocol Used at All Participating Sites

Sequence	Isotropic Resolution (mm)	TR/TE	Acquisition Time	Other Parameters
Precontrast T2-weighted FLAIR	1.0	4800/352	7 min 9 s	TI = 1800 ms
Pre- and postcontrast T2*-weighted segmented EPI	0.65	64/35	5 min 48 s	Flip angle = 10°, EPI factor = 15
Pre- and postcontrast T1-weighted imaging	1.0	7.8/3.0	3 min 16 s	Flip angle = 18°

Note—All sequences comprised a 3D sagittal acquisition of entire brain. TI = inversion time, EPI = echo-planar imaging.