Table 1.
Summary of the included studies.
| Reference | Number/Age (mean) | Cancer type/FIGO stage | Sarcopenia Criteria Cutoff (prevalence) | Progression-Free Survival | Overall Survival (HR, 95%CI) | Newcastle-Ottawa scale |
|---|---|---|---|---|---|---|
| Aust et al, 2015 (19) | N=140/60 | Ovarian/I-IV | SMI 41cm2/m2 (28.9%) (CT scan at L3 level) |
1.31 (0.76–2.26) | 1.23 (0.61–2.48) | 8 |
| Bronger et al, 2017 (13) | N=128/63 | Ovarian/III-IV | SMI 38.5 cm2/cm2 (11%) (CT scan at L3 level) |
2.52 (1.10-5.81) | 2.89 (1.11–7.54) | 7 |
| Chae et al, 2021 (21) | N=82/52 | Ovarian/I-II | SMI 38.7 cm2/cm2 (20.7%) (CT scan at L3 level) |
– | 58.4 (3.02–1,127.9) | 8 |
| de Paula et al, 2019 (22) | N=232/64.3 | Endometrial/I-IV | SMI 38.9 cm2/cm2 (25.8%) (CT scan at L3 level) |
– | 2.23 (1.19–4.20) | 7 |
| Ganju et al, 2020 (23) | N=64/61 | Endometrial/III-IV | SMI 41cm2/m2 (44%) | – | 3.02 (1.04–8.74) | 6 |
| Kim et al, 2020 (20) | N = 179/57.5 | Ovarian/III-IV | SMI 39.0 cm2/cm2 (42.5%) (CT scan at L3 level) |
1.292 (0.906–1.843) | 0.870 (0.488–1.550) | 7 |
| Kiyotoki et al, 2018 (24) | N = 60/56.1 | Cervical Cancer/I-IV | SMI and IM determined from the mean value 90.29 cm2 and 10.07 cm2 | 1.62 (0.53-4.97) | 2.89 (0.74-11.24) | 6 |
| Lee et al, 2018 (25) | N = 245/63 | Cervical Cancer/I-IV | SMI 41 cm2/cm2 (51.8%) (CT scan at L3 level) |
– | 6.02 (3.04–11.93) | 8 |
| Brooks et al, 2019 (26) | N = 148/54.3 | Endometrial/III | SMI 39.3 cm2/cm2 (33.6%) (CT scan at L3 level) |
0.67 (0.27–1.70) | 0.67 (0.29–1.52) | 7 |
| Matsubara et al, 2019 (17) | N=92/55.3 | Ovarian/I-IV | SMA <92.92 cm2 (50%) (CT scan at L3 level) |
1.272 (0.725-2.230) (univariate) |
2.186 (1.057-4.518) (univariate) | 8 |
| Rutten et al, 2017 (27) | 150/67 | Ovarian/II-IV | SMA > 2%/100 days (NR) | 1.698 (1.038–2.778) | 6 | |
| Rutten et al, 2017 (28) | N =216/63.1 | Ovarian/II-IV | SMI 38.73 cm2/cm2 (32.4%) (CT scan at L3 level) |
– | 1.362 (0.968-1.916) | 6 |
| Rutten et al, 2016 (29) | N=123/66.5 | Ovarian/II-IV | SMI 41.5cm2/m2 (67.5%) (CT scan at L3 level) |
1.773 (1.018–3.088) | 6 | |
| Yoshikawa et al, 2020 (30) | N = 40/56.9 | Cervical Cancer/IV | PMI: 3.72 cm2/m2
(CT scan at L3 level) |
– | 4.55 (1.36–18.21) | 6 |
| Yoshikawa et al, 2021 (31) | N = 72/62 | Ovarian/I-IV | PMI: 5.4 cm2/m2 (50%) (CT scan at L5 level) |
– | 3.87 (1.37−12.1) | 7 |
| Yoshino et al, 2020 (32) | N = 60/63.5 | Ovarian/I-IV | SMI 39 cm2/cm2 (60%) (CT scan at L3 level) |
– | 3.17 (1.18-9.06) | 6 |
FIGO, International Federation for Gynecologic Oncology.
SMI, skeletal muscle index.
IM, iliopsoas muscle.
PMI, Psoas muscle index.