Table 2.
Treatments and outcomes according to hospital survivability of patients with sepsis
| Variables | All cases | Survived | Died | P value* |
| Completion of the sepsis bundle of care | n=241 | n=146 | n=95 | |
| Completion of the sepsis bundle within 1 hour, no. (%) | 87 (36.1) | 53 (36.3) | 34 (35.8) | 0.936 |
| Completion of the initial administration of antibiotics within 1 hour, no. (%) | 173 (71.8) | 109 (74.7) | 64 (63.4) | 0.219 |
| Completion of the sepsis bundle within 3 hours, no. (%) | 108 (44.8) | 66 (45.2) | 42 (44.2) | 0.879 |
| Completion of the initial administration of antibiotics within 3 hours, no. (%) | 205 (85.1) | 131 (89.7) | 74 (77.9) | 0.012 |
| Life-sustaining treatments | n=251 | n=150 | n=101 | |
| Respiratory support, no. (%) | ||||
| Mechanical ventilation | 173 (68.9) | 82 (54.7) | 91 (90.1) | <0.001 |
| Non-invasive ventilation | 20 (8.0) | 13 (8.7) | 7 (6.9) | 0.618 |
| High-flow nasal oxygen | 38 (15.1) | 29 (19.3) | 9 (8.9) | 0.024 |
| Additional ICU support, no. (%) | ||||
| Vasopressors/inotropes | 163 (64.7) | 82 (54.3) | 81 (80.2) | <0.001 |
| Renal replacement therapy | 101 (40.2) | 43 (28.7) | 58 (57.4) | <0.001 |
| Red blood cell transfusion | 93 (37.1) | 48 (32.0) | 45 (44.6) | 0.043 |
| Platelet transfusion | 50 (19.9) | 20 (13.3) | 30 (29.7) | 0.001 |
| Fresh frozen plasma transfusion | 58 (23.1) | 28 (18.7) | 30 (29.7) | 0.042 |
| Surgical source control | 25 (10.0) | 19 (12.7) | 6 (5.9) | 0.081 |
| Non-surgical source control | 78 (31.1) | 54 (36.0) | 24 (23.8) | 0.040 |
| Outcomes | n=252 | n=151 | n=101 | |
| Patient status, no. (%) | <0.001† | |||
| Alive on current hospital discharge | 150 (59.5) | 150 (99.3) | 0 (0.0) | |
| Alive on discharge from current ICU stay, but died in current hospital stay | 17 (6.7) | 0 (0.0) | 17 (16.8) | |
| Alive on discharge from current ICU stay, but still in current hospital stay after 90 days | 1 (0.4) | 1 (0.7) | 0 (0.0) | |
| Still in current ICU stay after 90 days | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
| Died in current ICU stay | 84 (33.3) | 0 (0.0) | 84 (83.2) | |
| Length of stay, median days (IQR) | ||||
| Hospital | 16 (10–25) | 17 (11–24.25) | 13 (7–26) | 0.027‡ |
| ICU | 10 (6–18) | 6–1710.5 (6-17) | 10 (5–21) | 0.740‡ |
See tables S5–S7 (online supplemental file 3) for additional information.
*Comparison between the patients who survived and died using χ2 test.
†Fisher’s exact test.
‡Mann–Whitney U test.
ICU, intensive care unit; no, number.