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Male NZM2328 mice lack inflammatory signature enrichment associated with progression to chronic GN. (A) Heatmap of GSVA scores for enrichment of immune cell and pathway gene signatures in glomeruli of male CTL and AGN mice. Asterisks indicate significant comparisons with CTL mice. (B) GSVA enrichment of podocytes in cohorts shown in (A). (C) GSVA enrichment of signatures for estrogen-regulated and androgen-regulated genes in glomeruli of female and male AGN mice. *p<0.05, **p<0.01.
